Selective detection of sulfur-containing compounds by gas chromatography/chemical reaction interface mass
M Moini1, D Chace, F P Abramson
1Department of Pharmacology, The George Washington University Medical Center, 20037, Washington, DC.
Abstract:
Addition of a reactant gas to a low pressure microwave-induced plasma creates a reaction interface in which complex molecules are converted into small polyatomic neutral species. For a given reactant gas the array of these small molecules reflect s the elemental composition of the original analyte. In this study HCI has been found highly effective as a reactant gas for selective detection of sulfur-eontaining compounds using capillary gas chromatography/ chernical reaction interface mass spectrometry. Detection limits as low as 30 pg of a sulfur-containing compound and a dynamic range of two orders of magnitude were achieved.
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