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Assembly and Characterization of Polyelectrolyte Complex Micelles
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Electrostatically driven complexation of liposomes with a star-shaped polyelectrolyte to low-toxicity multi-liposomal

Alexander A Yaroslavov1, Andrey V Sybachin, Olga V Zaborova

  • 1Lomonosov Moscow State University, Chemistry Department, Leninskie Gory 1-3, 119991, Moscow, Russia.

Macromolecular Bioscience
|November 19, 2013
PubMed

Keywords:
drug delivery systemsliposomesphospholipidspolyelectrolytesstar polymers

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Micelle formation is an intricate process that hinges on the properties of amphiphilic or amphipathic molecules and the conditions of the system in which they are found. Amphiphilic molecules, which have both hydrophilic (water-attracting) and hydrophobic (water-repelling) parts, play a critical role in this process.In aqueous environments, these molecules arrange themselves such that their hydrophilic heads are turned towards the water phase, while their hydrophobic tails are oriented away...
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