Generation of slow phase-locked oscillation and variability of the interspike intervals in globally coupled neuronal oscillators
Related Experiment Video
Updated: May 5, 2026

Generation of Local CA1 γ Oscillations by Tetanic Stimulation
Published on: August 14, 2015
Ryotaro Tsuneki1, Shinji Doi, Junko Inoue
1Graduate School of Engineering, Kyoto University, Kyoto 615-8510, Japan. tneki716@rotary.kuee.kyoto-u.ac.jp.
Abstract:
To elucidate how a biological rhythm is regulated, the extended (three-dimensional) Bonhoeffer-van der Pol or FitzHugh-Nagumo equations are employed to investigate the dynamics of a population of neuronal oscillators globally coupled through a common buffer (mean field). Interesting phenomena, such as extraordinarily slow phase-locked oscillations (compared to the natural period of each neuronal oscillator) and the death of all oscillations, are observed. We demonstrate that the slow synchronization is due mainly to the existence of "fast" oscillators. Additionally, we examine the effect of noise on the synchronization and variability of the interspike intervals. Peculiar phenomena, such as noise-induced acceleration and deceleration, are observed. The results herein suggest that very small noise may significantly influence a biological rhythm.
Related Concept Videos
Muscle Stimulation Frequency
Wave summation
At low firing rates, motor neurons induce individual twitch contractions in muscle fibers. These twitches...
Propagation of Action Potentials
Neurons (nerve cells) have a resting membrane potential, with a slightly negative charge inside compared to outside. This is maintained by ion channels, such as sodium (Na+) and potassium (K+) channels, which control the flow of ions. When a stimulus, like a touch or a signal from another neuron, triggers the neuron, sodium channels open, allowing sodium ions to...
Action Potential: Phases of Stimulation
Resting Phase:
In this phase, the cell's membrane is at its resting potential, typically around -70 millivolts (mV) for neurons. Inside the cell, there is a higher concentration of potassium ions (K+) and a lower concentration of sodium ions (Na+). Voltage-gated sodium channels are closed, and...
Oscillations In An LC Circuit
Generation of Action Potential in Skeletal Muscles
Like neurons, muscle cells are also regarded as excitable due to their capacity to change in response to stimuli, primarily due to voltage-gated ion channels embedded in their plasma membranes, which get activated by alterations in the...
Resting Potential Decay
At rest, the K+ is the main ion that moves across the membrane...

