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Association between ischemic stroke and migraine in elderly Chinese: a case-control study
1Department of Neurology, Municipal Hospital of Taizhou, Jiaojiang, Zhejiang 318000, China. lhjyy@126.com.
BMC Geriatrics
|November 20, 2013
Summary
Migraine is significantly more common in elderly Chinese individuals with acute cerebral infarction (ACI) than in those without stroke. Migraine without aura is the predominant type, with lesions often in the anterior brain circulation.
Area of Science:
- Neurology
- Epidemiology
- Vascular Medicine
Background:
- Migraine and cerebrovascular disease are increasingly recognized as comorbid conditions.
- Limited data exists on the association between migraine and cerebrovascular disease in elderly Chinese populations.
- This study investigates migraine prevalence and characteristics in elderly Chinese patients with acute cerebral infarction (ACI).
Purpose of the Study:
- To determine the prevalence of migraine in elderly Chinese patients with ACI.
- To analyze lesion characteristics and stroke subtypes in ACI patients with comorbid migraine.
- To compare migraine prevalence between ACI patients and a matched control group.
Main Methods:
- A prospective case-control study involving 968 ACI patients (aged 55-70) and 1024 controls.
- Migraine diagnosis based on International Headache Society criteria, medical records, and questionnaires.
- Analysis of stroke subtypes (using Chinese Ischemic Stroke Subclassification) and lesion locations.
Main Results:
- Migraine prevalence was significantly higher in ACI patients (17.15%) compared to controls (3.9%) (P < 0.01).
- Migraine without aura constituted over 80% of cases in both groups.
- Large artery atherosclerosis was the most common ischemic lesion subtype (65.06%) in ACI patients with migraine.
Conclusions:
- Migraine is significantly more prevalent in elderly Chinese individuals with ACI than in those without.
- Migraine without aura is the predominant form of migraine in this population.
- Ischemic lesions in ACI patients, with or without migraine, predominantly affect the anterior cerebral circulation.
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