Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Structure and Function of Platelets01:18

Structure and Function of Platelets

7.2K
The cell fragments known as platelets are disc-shaped, with an average diameter of about 3 μm and a thickness of roughly 1 μm. They play a crucial role in the body's vascular clotting system, which also involves plasma proteins, blood cells, and blood vessel tissues.
Platelets are continually replenished, circulating in the bloodstream for 9-12 days before being removed by phagocytes, primarily in the spleen. A microliter of circulating blood contains between 150,000 and 450,000...
7.2K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Effects of Acute Exercise and 12-Week High-Intensity Interval Training on Inflammatory Biomarkers in Stable Coronary Artery Disease: A Randomized Controlled Trial.

Journal of the American Heart Association·2026
Same author

Apixaban Concentrations and Effects on Coagulation in Patients With Nephrotic Syndrome.

Kidney medicine·2025
Same author

Psychometric properties of patient-related outcome measures used for patients surviving a pulmonary embolism: A systematic review.

Thrombosis research·2025
Same author

MicroRNA dynamics and their link to platelet function following acute ST-segment elevation myocardial infarction.

Thrombosis research·2025
Same author

European Journal of Heart Failure consensus statement. Heart failure pharmacotherapy for patients with heart failure with reduced ejection fraction and concomitant atrial fibrillation: Review of evidence and call to action.

European journal of heart failure·2025
Same author

Development of a questionnaire investigating the physical and psychological well-being and need for rehabilitative strategies in patients with pulmonary embolism.

Journal of patient-reported outcomes·2025

Related Experiment Video

Updated: May 5, 2026

Dynamic Multiparameter Platelet Function Assessment Using a Capacitive Biosensor
06:32

Dynamic Multiparameter Platelet Function Assessment Using a Capacitive Biosensor

Published on: May 2, 2025

930

Rapid evaluation of platelet function using the Multiplate® Analyzer.

Morten Würtz1, Anne-Mette Hvas, Kristian Hylleberg Christensen

  • 1Department of Cardiology, Aarhus University Hospital , Denmark and.

Platelets
|November 20, 2013
PubMed
Summary

Rapid platelet function testing using the Multiplate® Analyzer is reliable within 5 minutes. This allows for quicker assessment of bleeding risk in patients, potentially improving treatment during procedures.

Keywords:
Aspirinbleedingcoronary artery diseaseimpedance aggregometryplatelet aggregationplatelet function tests

More Related Videos

Analyzing Platelet Subpopulations by Multi-color Flow Cytometry
08:04

Analyzing Platelet Subpopulations by Multi-color Flow Cytometry

Published on: June 10, 2025

2.1K
Microfluidics in Assessing Platelet Function
06:47

Microfluidics in Assessing Platelet Function

Published on: November 8, 2024

1.7K

Related Experiment Videos

Last Updated: May 5, 2026

Dynamic Multiparameter Platelet Function Assessment Using a Capacitive Biosensor
06:32

Dynamic Multiparameter Platelet Function Assessment Using a Capacitive Biosensor

Published on: May 2, 2025

930
Analyzing Platelet Subpopulations by Multi-color Flow Cytometry
08:04

Analyzing Platelet Subpopulations by Multi-color Flow Cytometry

Published on: June 10, 2025

2.1K
Microfluidics in Assessing Platelet Function
06:47

Microfluidics in Assessing Platelet Function

Published on: November 8, 2024

1.7K

Area of Science:

  • Cardiovascular Medicine
  • Hematology
  • Clinical Diagnostics

Background:

  • Platelet function testing is crucial for managing bleeding during surgical and interventional procedures.
  • Current recommendations involve a 30-minute waiting period for platelet function analysis.

Purpose of the Study:

  • To evaluate the reliability of platelet function testing performed 5 minutes after blood sampling using the Multiplate® Analyzer.
  • To compare rapid (5-minute) results with standard (30-minute) results.

Main Methods:

  • Platelet aggregometry was performed on 48 patients with diabetes and coronary artery disease on aspirin, and 50 healthy controls.
  • The Multiplate® Analyzer was used with arachidonic acid, collagen, and adenosine diphosphate (ADP) agonists at 5 and 30 minutes post-sampling.
  • Aspirin compliance was confirmed via serum thromboxane B2 measurements.

Main Results:

  • Platelet aggregation levels measured at 5 minutes strongly correlated with those measured at 30 minutes (r=0.75-0.89, p<0.0001).
  • 5-minute measurements showed slightly lower aggregation levels (4-8%) and greater variability compared to 30-minute measurements.
  • Weak but significant correlations were found between platelet aggregation and platelet count.

Conclusions:

  • The 30-minute waiting period for Multiplate® Analyzer testing can be omitted.
  • Rapid 5-minute platelet function testing provides reliable results, enabling faster on-site clinical decisions.
  • This rapid testing facilitates timely tailoring of treatment for bleeding patients.