Validation of near infrared spectroscopy to measure abdominal somatic tissue oxygen saturation in neonates
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Updated: May 5, 2026

How to Administer Near-Infrared Spectroscopy in Critically ill Neonates, Infants, and Children
Published on: August 19, 2020
M M Said1, N Niforatos, K Rais-Bahrami
1Children's National Medical Center and Department of Neonatology, The George Washington University School of Medicine, Washington, D.C., USA.
Objective:
In this study, we validated the use of the FORE-SIGHT® (CAS Medical Systems, Branford, CT USA) tissue oximeter monitor on abdominal tissue oxygenation in infants ≤4 kg using a stool-interference compensation algorithm.
Study Design:
A total of 40 neonates with an umbilical venous catheter (UVC) were enrolled in this study. We measured abdominal tissue saturation (StO2) values using FORE-SIGHT, and compared to a Reference StO2 value derived from weighted co-oximetry values from the UVC and pulse oximeter measurements.
Results:
There was a strong correlation between NIRS calculated StO2 measurements when compared with the reference StO2, with an overall bias (sd) of -0.77 (5.06)% and a concordance correlation coefficient (CCC) of 0.789.
Conclusion:
Data from this validation study suggest that the FORE-SIGHT monitor, which compensates for the optical properties of stools in neonates, can yield accurate measures of abdominal tissue oxygen saturation.
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