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Aip1p Dynamics Are Altered by the R256H Mutation in Actin
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Genetics of actin-related sequences in tomato

R Bernatzky1, S D Tanksley

  • 1Department of Horticulture and Plant Genetic Engineering Laboratory, New Mexico State University, 88003, Las Cruces, NM, USA.

TAG. Theoretical and Applied Genetics. Theoretische Und Angewandte Genetik
|November 20, 2013
PubMed

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Actin is a family of globular proteins that are highly abundant in eukaryotic cells. It makes up approximately 1-5% of total cell protein concentration. Actin monomers polymerize to form a complex network of polarized filaments, the actin cytoskeleton, that plays a crucial role in many cellular processes, including cell motility, division, endocytosis, and metastasis of cancer cells.
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Actin polymerization occurs through the head-to-tail association of binding sites on monomeric actin or G-actin to form filamentous or F-actin. The polymerization can be divided into three phases ̶  nucleation, elongation, and steady-state phase.
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