Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Long-Range Transverse-Momentum Correlations and Radial Flow in Pb-Pb Collisions at the LHC.

Physical review letters·2026
Same author

Search for Quasiparticle Scattering in the Quark-Gluon Plasma with Jet Splittings in pp and Pb-Pb Collisions at sqrt[s_{NN}]=5.02  TeV.

Physical review letters·2025
Same author

First Measurement of A=4 Hypernuclei and Antihypernuclei at the LHC.

Physical review letters·2025
Same author

Otitis Media With Effusion (OME) and Eustachian Tube Dysfunction: The Role of Allergy and Immunity-An EAACI Position Paper.

Allergy·2025
Same author

EUFOREA meeting on defining disease states in allergic rhinitis: towards a unified language in AR.

Frontiers in allergy·2025
Same author

Probing Strangeness Hadronization with Event-by-Event Production of Multistrange Hadrons.

Physical review letters·2025

Related Experiment Video

Updated: May 5, 2026

A Non-invasive Way to Isolate and Phenotype Cells from the Conjunctiva
07:35

A Non-invasive Way to Isolate and Phenotype Cells from the Conjunctiva

Published on: July 5, 2017

14.2K

Objectifying the conjunctival provocation test: photography-based rating and digital analysis.

S Dogan1, A Astvatsatourov, T M Deserno

  • 1Institute of Medical Statistics, Informatics and Epidemiology, University Hospital Cologne, Cologne, Germany.

International Archives of Allergy and Immunology
|November 20, 2013
PubMed
Summary
This summary is machine-generated.

Digital image analysis offers an objective method for evaluating conjunctival provocation tests (CPT) in allergic rhinoconjunctivitis. This approach shows potential for standardizing CPT results, improving diagnostic accuracy.

More Related Videos

Comparing Objective Conjunctival Hyperemia Grading and the Ocular Surface Disease Index Score in Dry Eye Syndrome During COVID-19
06:29

Comparing Objective Conjunctival Hyperemia Grading and the Ocular Surface Disease Index Score in Dry Eye Syndrome During COVID-19

Published on: May 25, 2022

2.2K
Fabrication and Surgical Application of Enriched Photo-crosslinked Gelatin–Riboflavin Hydrogels for Corneal Wound Repair in Rabbits
05:53

Fabrication and Surgical Application of Enriched Photo-crosslinked Gelatin–Riboflavin Hydrogels for Corneal Wound Repair in Rabbits

Published on: April 24, 2026

19

Related Experiment Videos

Last Updated: May 5, 2026

A Non-invasive Way to Isolate and Phenotype Cells from the Conjunctiva
07:35

A Non-invasive Way to Isolate and Phenotype Cells from the Conjunctiva

Published on: July 5, 2017

14.2K
Comparing Objective Conjunctival Hyperemia Grading and the Ocular Surface Disease Index Score in Dry Eye Syndrome During COVID-19
06:29

Comparing Objective Conjunctival Hyperemia Grading and the Ocular Surface Disease Index Score in Dry Eye Syndrome During COVID-19

Published on: May 25, 2022

2.2K
Fabrication and Surgical Application of Enriched Photo-crosslinked Gelatin–Riboflavin Hydrogels for Corneal Wound Repair in Rabbits
05:53

Fabrication and Surgical Application of Enriched Photo-crosslinked Gelatin–Riboflavin Hydrogels for Corneal Wound Repair in Rabbits

Published on: April 24, 2026

19

Area of Science:

  • Ophthalmology
  • Allergology
  • Medical Imaging

Background:

  • Allergic rhinoconjunctivitis presents with both nasal and ocular symptoms.
  • The conjunctival provocation test (CPT) is used to assess allergen reactivity.
  • Current CPT interpretation lacks standardized guidelines and objective evaluation methods.

Purpose of the Study:

  • To establish digital analysis of macroimages as an objective, validated, and standardized method for interpreting CPT results.
  • To compare digital image analysis with traditional subjective assessment methods.

Main Methods:

  • A clinical immunotherapy trial involving 155 patients documented treatment progress using CPT.
  • Local investigators used subjective symptom scores; a central observer rated conjunctival hyperemia via digital photography.
  • Digital image analysis software quantified conjunctival hyperemia from photographs.

Main Results:

  • Spearman's correlation between investigators and central observer was r=0.729 (p<0.001).
  • Digital image analysis showed high agreement (69%) with the central observer but low agreement (38%) with local investigators.
  • Correlation for digital analysis with the central observer was r=0.264, and with investigators was r=0.064.

Conclusions:

  • Photography-based central observer rating can supplement local investigator assessment for objective CPT evaluation.
  • Digital image analysis demonstrates potential as an objective method, contrasting with current subjective investigator-based evaluations.