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Matrix-assisted Autologous Chondrocyte Transplantation for Remodeling and Repair of Chondral Defects in a Rabbit Model
Published on: May 21, 2013
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Lower recurrence rate in chondroblastoma using extended curettage and cryosurgery
Mohamed Ahmed Mashhour1, Mohamed Abdel Rahman
1Department of Orthopaedic Surgery, Orthopaedic Oncology Unit, Faculty of Medicine, Ain Shams University, Abbasseia Square, Cairo, Egypt, mohamed.mashhour@gmail.com.
International Orthopaedics
|November 20, 2013
Summary
This study shows that extended curettage with cryotherapy and bone grafting effectively treats aggressive chondroblastoma, significantly reducing local recurrence rates for this bone tumor.
Area of Science:
- Orthopedic Oncology
- Surgical Oncology
- Bone Tumors
Background:
- Chondroblastoma is an aggressive benign bone tumor.
- Local recurrence remains a significant challenge in chondroblastoma management.
- Existing treatments like curettage and bone grafting have limitations in preventing recurrence.
Purpose of the Study:
- To evaluate the efficacy of intraregional extended curettage combined with adjuvant cryotherapy and autogenous bone grafting for chondroblastoma.
- To assess the potential of this combined treatment to decrease the local recurrence rate.
- To analyze functional outcomes following this treatment protocol.
Main Methods:
- Patients underwent intralesional extended curettage.
- Adjuvant cryotherapy using liquid nitrogen was applied.
- Autogenous iliac crest bone grafting was performed.
- Follow-up included clinical and radiological assessments for healing and recurrence.
- Functional outcomes were measured using the Musculoskeletal Tumour Society (MSTS) scoring system.
Main Results:
- Mean follow-up was 49 months.
- Local recurrence rate was 7.1%.
- Average bone healing time was 7.4 months.
- Mean MSTS functional score was 92.7%.
- Complications included physeal growth arrest (14.3%) and superficial skin sloughing (7.1%).
Conclusions:
- The combination of extended curettage, cryotherapy, and autogenous bone grafting is a reliable treatment for chondroblastoma.
- This method achieves a low rate of local recurrence.
- The treatment provides good functional outcomes for patients with chondroblastoma.

