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Antisocial personality disorder is a chronic mental health condition characterized by persistent patterns of disregard for the rights and well-being of others. Individuals with antisocial personality disorder exhibit behaviors that include deceitfulness, impulsivity, irresponsibility, aggression, and a profound lack of empathy. These traits often manifest early in life and persist into adulthood, leading to significant personal, social, and legal consequences.
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Antisocial personality disorder: a current review.

Andrea L Glenn1, Alexandria K Johnson, Adrian Raine

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This review examines antisocial personality disorder (ASPD), exploring its subtypes, genetic and environmental causes, and brain imaging findings. Preliminary treatments for ASPD are also discussed.

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Area of Science:

  • Psychiatry
  • Psychology
  • Neuroscience

Background:

  • Antisocial personality disorder (ASPD) is defined in the DSM-5 by repetitive irresponsible, delinquent, and criminal behavior.
  • The ASPD diagnosis is controversial due to heterogeneity, overinclusivity, and overlap with other disorders.

Purpose of the Study:

  • To review recent research enhancing the understanding of ASPD characteristics, subtypes, and comorbid conditions.
  • To discuss the etiology of ASPD, including genetic and environmental factors.
  • To explore brain imaging findings related to ASPD and other psychopathology, and review preliminary treatment research.

Main Methods:

  • Literature review of recent studies on ASPD.
  • Analysis of research on ASPD subtypes and comorbidities.
  • Examination of etiological factors (genetic, environmental) and neuroimaging studies.
  • Review of preliminary treatment outcome research for ASPD.

Main Results:

  • Recent studies reveal distinct subtypes of individuals meeting ASPD criteria.
  • Comorbid conditions significantly influence the clinical presentation of ASPD.
  • Genetic and environmental factors are implicated in the development and persistence of antisocial behavior.
  • Brain imaging research clarifies relationships between ASPD and other psychopathology.

Conclusions:

  • Further research is needed to refine the understanding and diagnosis of ASPD.
  • Identifying subtypes and understanding comorbidities can improve treatment approaches.
  • Etiological and neurobiological insights offer potential avenues for novel interventions for antisocial behavior.