Preoperative chemotherapy in head and neck cancer

We submit our present work dealing with stage III and IV epidermoid head and neck carcinomas which have been referred for preoperative chemotherapy. Our selection of one of the two following combinations is based on the histological differentiation of the tumour and general state of the patient. Intravenous Bleomycin plus intratumoral oil Bleomycin, or Continuous infusion of Cisplatin and 5 Fluoro-uracil for six days. We present the results obtained in 37 patients, and the complications which arose.