Related Experiment Video
Updated: May 5, 2026
Measuring the Motor Aspect of Cancer-Related Fatigue using a Handheld Dynamometer
Published on: February 20, 2020
Evaluation of the Persian version of modified fatigue impact scale in Iranian patients with multiple sclerosis
Mohammad Hossein Harirchian1, Somayeh Nasergivechi, Marzieh Maddah
1Professor, Iranian Center of Neurological Research, Department of Neurology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran.
Background:
Fatigue, a major cause of disability in individuals with multiple sclerosis (MS), is associated with reduced quality of life. The aim of this study was to evaluate the reliability and reproducibility of the Persian version of Modified Fatigue Impact Scale (MFIS) in Iranian patients with MS.
Methods:
This study included 15 subjects with clinically definite MS, 15 hospitalized patients with MS, and 15 hospitalized patients with other chronic illnesses (as controls). They filled in the Persian version of the MFIS twice with a three-day interval. MFIS items were analyzed and the correlation coefficient was calculated.
Results:
THERE WAS A GOOD CORRELATION BETWEEN THE SCORES OF THE TWO MEASUREMENTS (CORRELATION COEFFICIENT: 0.984, P < 0.001) especially in physical and cognitive subgroups. The reproducibility of psychosocial subscale was lower than physical and cognitive subscales.
Conclusion:
According to our findings, the Persian version of the MFIS has a good reliability and reproducibility for assessment of fatigue in patients with MS.
Insights
The Persian version of the Modified Fatigue Impact Scale (MFIS) demonstrates good reliability and reproducibility for assessing fatigue in multiple sclerosis (MS) patients. This validated tool aids in understanding the impact of MS fatigue on quality of life.
Area of Science:
- Neurology
- Rehabilitation Medicine
- Psychometrics
Background:
- Fatigue is a primary cause of disability and reduced quality of life in multiple sclerosis (MS) patients.
- The Modified Fatigue Impact Scale (MFIS) is a crucial tool for measuring fatigue's impact.
- Validating the Persian version of the MFIS is essential for Iranian MS patient populations.
Purpose of the Study:
- To evaluate the reliability and reproducibility of the Persian version of the Modified Fatigue Impact Scale (MFIS).
- To assess the suitability of the Persian MFIS for measuring fatigue in Iranian patients with multiple sclerosis (MS).
Main Methods:
- The study involved 45 participants: 15 with definite MS, 15 hospitalized MS patients, and 15 controls with other chronic illnesses.
- Participants completed the Persian MFIS twice, with a three-day interval between assessments.
- Statistical analysis, including correlation coefficients, was used to determine reliability and reproducibility.
Main Results:
- A strong correlation (coefficient: 0.984, P < 0.001) was found between the two MFIS measurements, indicating good reliability.
- The physical and cognitive subscales showed higher reproducibility compared to the psychosocial subscale.
- The Persian MFIS proved to be a reliable instrument for assessing fatigue in MS.
Conclusions:
- The Persian version of the MFIS exhibits good reliability and reproducibility for assessing fatigue in multiple sclerosis patients.
- This validated scale can be effectively used in clinical practice and research involving Iranian MS populations.
- The findings support the use of the Persian MFIS to improve the management of fatigue in MS.
