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Chorea and retinal vessel occlusion in a patient with systemic lupus erythematosus

Vahid-Reza Ostovan1, Askar Ghorbani

  • 1Department of Neurology, Shariati Hospital, Tehran University of Medical Sciences AND Iranian Center of Neurological Research, Tehran, Iran.

Iranian Journal of Neurology
|November 20, 2013
PubMed

Insights

This case report details a patient with antiphospholipid syndrome (APS) and systemic lupus erythematosus (SLE) who experienced both chorea and retinal vessel occlusion. These rare, co-occurring neurological complications highlight the diverse manifestations of APS and SLE.

Area of Science:

  • Neurology
  • Rheumatology
  • Ophthalmology

Background:

  • Antiphospholipid syndrome (APS) is an autoimmune disorder associated with aPL antibodies, leading to various neurological complications.
  • Systemic lupus erythematosus (SLE) can also present with neurological issues, and its association with APS is well-documented.

Observation:

  • A 27-year-old male presented with involuntary movements (chorea), slurred speech, and vision loss in his right eye.
  • Clinical investigations confirmed the diagnoses of both SLE and APS.

Findings:

  • The patient exhibited concomitant chorea and retinal vessel occlusion, a rare combination of neurological and ocular manifestations.
  • Treatment involved anticoagulants and immunosuppressants, including prednisolone, leading to clinical improvement.

Implications:

  • This case underscores the importance of recognizing the diverse and sometimes overlapping neurological manifestations of SLE and APS.
  • The co-occurrence of retinal vessel occlusion and chorea in this patient provides valuable insight into the complex pathophysiology of these conditions.
  • Early diagnosis and comprehensive treatment are crucial for managing patients with combined SLE and APS to prevent severe complications.

Keywords:
Antiphospholipid SyndromeChoreaRetinal Vessel OcclusionSystemic Lupus Erythematosus

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