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Identification of Sleeping Beauty Transposon Insertions in Solid Tumors using Linker-mediated PCR
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Domesticated transposable element gene products in human cancer

Jesse D Riordan1, Adam J Dupuy

  • 1Department of Anatomy & Cell Biology; Roy J. & Lucille A. Carver College of Medicine; University of Iowa; Iowa City, IA USA.

Mobile Genetic Elements
|November 20, 2013
PubMed
Summary

Transposable elements, or "jumping genes," can be domesticated by cells to perform new functions. Some of these domesticated genes are implicated in human cancer development and promote tumor growth.

Keywords:
LDOC1LDOC1LRtl1cancerdomesticated genesexaptationtransposons

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