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Hypophosphatemic rickets associated with giant hairy nevus
Sameer Aggarwal1, Nitya Nand Sharma, Dheeraj K Singhania
1Department of Medicine, PGIMS, Rohtak, Haryana, India.
Indian Journal of Endocrinology and Metabolism
|November 20, 2013
Summary
This study reports a rare case of hypophosphatemic rickets in a boy with a giant hairy nevus. This finding suggests a potential link between hairy nevi and this bone disorder.
Area of Science:
- Endocrinology
- Dermatology
- Pediatrics
Background:
- Epidermal nevus syndrome is a condition involving multiple organ systems.
- Congenital nevomelanocytic nevi (hairy nevi) are rarely associated with hypophosphatemic rickets.
- Phosphatonins, circulating factors causing phosphaturia, are hypothesized to be secreted by nevi.
Purpose of the Study:
- To report a rare case of hypophosphatemic rickets associated with a giant hairy nevus.
- To contribute to the understanding of the association between congenital nevi and metabolic bone diseases.
Main Methods:
- Case report of a 10-year-old boy.
- Clinical evaluation and diagnostic workup for hypophosphatemic rickets and giant hairy nevus.
Main Results:
- A 10-year-old boy presented with hypophosphatemic rickets.
- The patient had a co-existing giant hairy nevus.
- This case highlights a rare association between these conditions.
Conclusions:
- Giant hairy nevi may be associated with hypophosphatemic rickets.
- Further research is needed to elucidate the role of phosphatonins in this association.
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