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Resolution of "salt and pepper" appearance of the skull with vitamin D therapy
Gursimran Kaur1, Parminder Singh, Naveen Mittal
1Department of Internal Medicine (Endocrinology), Dayanand Medical College and Hospital, Ludhiana, Punjab, India.
Abstract:
Chronic hypovitaminosis D leads to state of decreased mineralization and generalized osteomalacia. It also results in secondary hyperparathyroidism causing increased bone turn over and decreased bone mass, manifested radiologically as a "salt and pepper" appearance in skull, subperiosteal resorption, bone cysts and lytic lesions. In this case, a young male patient with hypovitaminosis D and secondary hyperparathyroidism, radiological features show resolution of "salt and pepper" appearance of the skull with vitamin D in 11 months and regression of other lytic lesions.
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