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Invasive cranial mycosis our experiences

Tapas Kumbhkar1, Shaifali Bansal, Sushil Jindal

  • 1Department of General Medicine, Peoples College of Medical Sciences and Research Centre, Bhanpur, Bhopal, Madhya Pradesh, India.

Indian Journal of Endocrinology and Metabolism
|November 20, 2013
PubMed

Insights

Fungal cranial infections in immunocompromised and diabetic patients, often caused by Aspergillus and Mucor, lead to severe tissue destruction and high mortality. This study reviews six cases of these challenging infections.

Area of Science:

  • Mycology
  • Infectious Diseases
  • Neurosurgery

Background:

  • Fungal infections pose a significant threat to immunocompromised and diabetic individuals.
  • Cranial infections by fungi like Aspergillus and Mucor are particularly dangerous.

Observation:

  • These fungi invade and destroy adjacent cranial structures, including sinuses, orbit, and ethmoid regions.
  • Patients often present with severe symptoms due to extensive tissue damage.
  • High mortality and morbidity rates are observed despite aggressive multimodal treatment.

Findings:

  • The study details the clinical experience with six cases of invasive fungal cranial infections.
  • Common pathogens identified were Aspergillus and Mucor species.
  • Treatment involved combined surgical intervention, antifungal therapy, and diabetes management.

Implications:

  • Early diagnosis and aggressive treatment are crucial for managing invasive fungal sinusitis.
  • Understanding the patterns of tissue invasion is key to surgical planning.
  • Further research is needed to improve outcomes for these devastating infections.
Keywords:
Immunocompromised stateMycosiscomplete ophthalmoplegidiabetes

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