Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Chronic Kidney Disease III: Interprofessional Care01:28

Chronic Kidney Disease III: Interprofessional Care

706
Chronic kidney disease (CKD) requires collaborative and comprehensive management. CKD progresses through stages and can lead to end-stage kidney disease (ESKD) if untreated. Interprofessional collaboration and patient education are crucial, enabling patients to manage their health and improve their quality of life.Diagnostic approach for chronic kidney diseaseThe diagnosis of CKD primarily focuses on the glomerular filtration rate (GFR), which assesses kidney function by measuring how well...
706
Rheumatic Heart Disease IV: Nursing Management01:20

Rheumatic Heart Disease IV: Nursing Management

486
AssessmentA comprehensive assessment is essential in managing a patient with rheumatic heart disease (RHD). Begin with obtaining a detailed medical history, including recent streptococcal infections, a history of rheumatic fever, or previously diagnosed rheumatic heart disease. Assess the patient for symptoms such as fever, chest pain, widespread joint pain (arthralgia), tachycardia, pericardial friction rub, muffled heart sounds, heart murmurs, peripheral edema, subcutaneous nodules, and...
486
Urinary Tract Calculi IV: Nutrition Therapy and Prevention01:27

Urinary Tract Calculi IV: Nutrition Therapy and Prevention

764
Management of renal calculi focuses on effective strategies like tailored nutrition and hydration therapy. Adjusting diet and fluid intake reduces stone formation and recurrence, making these interventions simple yet powerful in kidney stone prevention and management.Understanding Kidney StonesKidney stones form when calcium, oxalate, uric acid, and cystine concentrate and crystallize in urine. Factors contributing to their formation include genetic predisposition, certain medical conditions,...
764
Acute Kidney Injury IV: Diagnostic Studies and Prevention01:30

Acute Kidney Injury IV: Diagnostic Studies and Prevention

582
Accurate diagnosis and effective prevention are critical in managing Acute Kidney Injury (AKI), which is linked to high mortality rates ranging from 10% to 80%. Timely recognition of at-risk patients and careful monitoring can significantly reduce the likelihood of kidney damage.Diagnostic Assessments:The diagnostic process starts with a comprehensive medical history to identify prerenal, intrarenal, and postrenal causes.Prerenal causes, such as dehydration, hypotension, or blood loss, should...
582
Rheumatic Heart Disease III: Medical Management01:21

Rheumatic Heart Disease III: Medical Management

548
Rheumatic heart disease (RHD) management can be divided into two main strategies: prevention and long-term management.Primary PreventionPrimary prevention focuses on timely diagnosis and management of group A streptococcal pharyngitis to prevent acute rheumatic fever. The most widely used antibiotic for treating this condition is intramuscular benzathine penicillin G.Acute Rheumatic Fever TreatmentThe primary treatment goal for a patient diagnosed with acute rheumatic fever is to suppress the...
548
Acute Kidney Injury I: Introduction01:22

Acute Kidney Injury I: Introduction

1.5K
Introduction:Acute Kidney Injury (AKI) describes a swift decrease in kidney function occurring over hours to days, characterized by the kidneys' failure to remove waste products from the bloodstream. This leads to dangerous complications like metabolic acidosis, fluid overload, and electrolyte imbalances, such as hyperkalemia, which can cause life-threatening arrhythmias. AKI is common in both hospital and outpatient settings, often triggered by dehydration, sepsis, or exposure to nephrotoxic...
1.5K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Screening Early Renal Disease Using Albuminuria in Indian Patients at High Risk.

Kidney international reports·2026
Same author

Pathophysiology of pregnancy-associated acute kidney injury.

Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association·2026
Same author

Humoral Response to COVID-19 Vaccines and Infection During Sibeprenlimab Treatment of IgA Nephropathy: Data from the ENVISION Trial.

Clinical journal of the American Society of Nephrology : CJASN·2026
Same author

MetaDilutionR: An R Package for Data-Driven Determination of Optimal Plasma Dilution in Untargeted Metabolomics to Achieve Maximum Metabolite Coverage with ESI Linearity.

Journal of the American Society for Mass Spectrometry·2026
Same author

The Design and Conduct of Cohort Studies of Peoples With CKD - International Perspectives From iNET-CKD.

Kidney international reports·2026
Same author

Sitagliptin, Metformin and Glimepiride Fixed-Dose Combination Compared to Co-Administration of Metformin and High-Dose Glimepiride in Indian Patients With Type 2 Diabetes: A Randomised, Double-Blind, Double-Dummy, Phase 3 Clinical Study.

Diabetes, obesity & metabolism·2026
Same journal

Development and Validation of a Comprehensive Obesity Assessment Tool: Integrating Lifestyle, Body Image, and Past Weight Management.

Indian journal of endocrinology and metabolism·2026
Same journal

The Indian Obesity Paradox- Low in Muscle, High in Fat.

Indian journal of endocrinology and metabolism·2026
Same journal

Serial Changes in Thyroid Hormones with Oral or Intravenous Bisphosphonates.

Indian journal of endocrinology and metabolism·2026
Same journal

Role of Serum Triiodothyronine-to-Thyroxine Ratio and Thyroid Colour Flow Doppler in Differentiation of Graves' Disease from Destructive Thyroiditis.

Indian journal of endocrinology and metabolism·2026
Same journal

Efficacy of Fixed Low-Dose Weekly Subcutaneous Testosterone Self-Administration in Transgender Male Patients in India.

Indian journal of endocrinology and metabolism·2026
Same journal

What Works in Type 2 Diabetes: Intermittent Fasting or Calorie Restriction or Both?

Indian journal of endocrinology and metabolism·2026
See all related articles

Related Experiment Video

Updated: May 5, 2026

5/6 Nephrectomy Using Sharp Bipolectomy Via Midline Laparotomy in Rats
05:34

5/6 Nephrectomy Using Sharp Bipolectomy Via Midline Laparotomy in Rats

Published on: April 4, 2025

1.8K

Renal rickets-practical approach.

Manisha Sahay1, Rakesh Sahay

  • 1Department of Nephrology, Osmania Medical College and General Hospital, Hyderabad, Andhra Pradesh, Haryana, India ; Osmania Medical College and General Hospital, Hyderabad, Andhra Pradesh, Haryana, India.

Indian Journal of Endocrinology and Metabolism
|November 20, 2013
PubMed
Summary
This summary is machine-generated.

Rickets and osteomalacia are common in tropical regions, often treatable with vitamin D and calcium. Some cases resist treatment due to kidney issues, requiring specific diagnosis and management.

Keywords:
Hypophosphatemic ricketsosteomalaciarenal ricketsrenal tubular acidosisricketsvitamin D rickets

More Related Videos

Establishment of a Simple and Effective Rat Model for Intraoperative Parathyroid Gland Imaging
07:12

Establishment of a Simple and Effective Rat Model for Intraoperative Parathyroid Gland Imaging

Published on: August 17, 2022

4.8K
Early Detection of Drug-Induced Renal Hemodynamic Dysfunction Using Sonographic Technology in Rats
06:38

Early Detection of Drug-Induced Renal Hemodynamic Dysfunction Using Sonographic Technology in Rats

Published on: March 11, 2016

13.2K

Related Experiment Videos

Last Updated: May 5, 2026

5/6 Nephrectomy Using Sharp Bipolectomy Via Midline Laparotomy in Rats
05:34

5/6 Nephrectomy Using Sharp Bipolectomy Via Midline Laparotomy in Rats

Published on: April 4, 2025

1.8K
Establishment of a Simple and Effective Rat Model for Intraoperative Parathyroid Gland Imaging
07:12

Establishment of a Simple and Effective Rat Model for Intraoperative Parathyroid Gland Imaging

Published on: August 17, 2022

4.8K
Early Detection of Drug-Induced Renal Hemodynamic Dysfunction Using Sonographic Technology in Rats
06:38

Early Detection of Drug-Induced Renal Hemodynamic Dysfunction Using Sonographic Technology in Rats

Published on: March 11, 2016

13.2K

Area of Science:

  • Endocrinology
  • Nephrology
  • Nutritional Science

Background:

  • Rickets and osteomalacia present significant health challenges in tropical environments.
  • Nutritional deficiencies, particularly low vitamin D and calcium intake, are common causes.
  • Some cases exhibit resistance to standard vitamin D therapy, indicating underlying renal pathologies.

Purpose of the Study:

  • To highlight the prevalence and causes of rickets and osteomalacia in tropical regions.
  • To differentiate between nutritionally responsive and refractory cases.
  • To emphasize the importance of diagnosing and managing renal-related rickets.

Main Methods:

  • Review of clinical cases presenting with rickets/osteomalacia.
  • Analysis of dietary and biochemical data.
  • Classification based on response to vitamin D and calcium therapy.
  • Identification of specific renal defects.

Main Results:

  • Many cases are successfully treated with calcium and vitamin D supplementation.
  • A subset of patients shows refractory symptoms, suggesting non-nutritional etiologies.
  • Renal tubular acidosis, hypophosphatemic rickets, and vitamin D-dependent rickets were identified.
  • Vitamin D-dependent rickets is linked to impaired 1α-hydroxylase activity in the kidneys.

Conclusions:

  • Rickets and osteomalacia in the tropics require careful etiological diagnosis.
  • Vitamin D-refractory cases necessitate investigation for underlying renal defects.
  • Specific treatments targeting renal pathways are crucial for refractory rickets/osteomalacia.