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Renal rickets-practical approach
1Department of Nephrology, Osmania Medical College and General Hospital, Hyderabad, Andhra Pradesh, Haryana, India ; Osmania Medical College and General Hospital, Hyderabad, Andhra Pradesh, Haryana, India.
Abstract:
Rickets/osteomalacia is an important problem in a tropical country. Many cases are due to poor vitamin D intake or calcium deficient diets and can be corrected by administration of calcium and vitamin D. However, some cases are refractory to vitamin D therapy and are related to renal defects. These include rickets of renal tubular acidosis (RTA), hypophosphatemic rickets, and vitamin D dependent rickets (VDDR). The latter is due to impaired action of 1α-hydroxylase in renal tubule. These varieties need proper diagnosis and specific treatment.
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