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Depressants01:28

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Depressant drugs, including alcohol and sedative-hypnotics, diminish central nervous system activity by enhancing the action of gamma-aminobutyric acid (GABA), a neurotransmitter that reduces brain activity and promotes relaxation. These substances can have various therapeutic uses but also pose significant risks, especially when misused or combined.
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Alcohols from Carbonyl Compounds: Reduction02:23

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This lesson delves into the concept of protection and deprotection of a functional group fundamental to synthetic organic chemistry. These phenomena are explained in the context of aliphatic and aromatic alcohols.
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Updated: May 5, 2026

Chronic Intermittent Ethanol Vapor Exposure Paired with Two-Bottle Choice to Model Alcohol Use Disorder
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Alcohol and psoriasis: sobering thoughts.

K Adamzik1, M A McAleer, B Kirby

  • 1Department of Dermatology, St. Vincent's University Hospital, Dublin, Ireland.

Clinical and Experimental Dermatology
|November 21, 2013
PubMed
Summary
This summary is machine-generated.

Psoriasis patients with moderate to severe disease show higher rates of alcohol-related health issues and death. Addressing alcohol use may improve outcomes for these patients.

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Area of Science:

  • Dermatology
  • Public Health
  • Internal Medicine

Background:

  • Psoriasis is a chronic autoimmune disease with significant systemic implications.
  • Evidence links moderate to severe psoriasis to increased alcohol-related comorbidities and mortality.
  • This association appears distinct from other autoimmune conditions.

Purpose of the Study:

  • To explore the complex relationship between psoriasis and alcohol consumption.
  • To highlight the potential impact of alcohol on psoriasis comorbidities.
  • To emphasize the need for screening and intervention regarding alcohol use in psoriasis patients.

Main Methods:

  • Review of epidemiological data on psoriasis, alcohol consumption, and related diseases.
  • Analysis of the impact of excessive alcohol intake on systemic inflammation.
  • Examination of alcohol's contribution to psoriasis comorbidities like cardiovascular disease and depression.

Main Results:

  • Patients with moderate to severe psoriasis exhibit a higher incidence of alcohol-related diseases and mortality.
  • Excessive alcohol consumption may exacerbate systemic inflammation and associated comorbidities.
  • The link between alcohol and adverse outcomes seems specific to psoriasis.

Conclusions:

  • A complex association exists between psoriasis and alcohol consumption.
  • Screening for hazardous alcohol use is recommended for patients with moderate to severe psoriasis.
  • Interventions targeting alcohol consumption may be beneficial in managing psoriasis and its comorbidities.