Sudden cardiac arrest in hemodialysis patients with wearable cardioverter defibrillator

Insights

Sudden cardiac arrest (SCA) survival is poor for hemodialysis (HD) patients. Wearable cardioverter defibrillators (WCDs) in HD patients showed improved post-SCA survival compared to historical data.

Area of Science:

  • Cardiology
  • Nephrology
  • Medical Devices

Background:

  • Sudden cardiac arrest (SCA) survival outcomes are poor for hemodialysis (HD) patients.
  • Characteristics of SCA and survival post-event in HD patients using wearable cardioverter defibrillators (WCDs) are not well understood.

Purpose of the Study:

  • To investigate the characteristics of SCA events in HD patients using WCDs.
  • To evaluate the post-SCA survival rates in HD patients treated with WCDs.

Main Methods:

  • Retrospective study of HD patients prescribed WCDs between 2004-2011 who experienced SCA.
  • Data collected on demographics, clinical background, and SCA event characteristics from manufacturer database.
  • Mortality determined using the Social Security Death Index.

Main Results:

  • 84 SCA events in 75 HD patients (mean age 62.9 years); 78.6% due to ventricular tachycardia/fibrillation.
  • Acute 24-hour survival was 70.7%, 30-day survival was 50.7%, and 1-year survival was 31.4%.
  • Women demonstrated significantly better post-SCA survival than men (HR=2.41, P=0.03).

Conclusions:

  • The use of WCDs in HD patients is associated with improved post-SCA survival.
  • Findings suggest WCDs may be a valuable tool for managing SCA risk in this population.
Abstract

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