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Crohn`s disease. Increasing trend in Saudi Arabia
Ibrahim A Al-Mofleh1, Nahlah A Azzam
1Department of Medicine, College of Medicine, PO Box 2925 (59), King Saud University, Riyadh 11461, Kingdom of Saudi Arabia. Tel. + 966 (11) 4679167. Fax. + 966 (11) 4671217. E-mail: ialmofleh@ksu.edu.sa / medicine_im@outlook.com.
Saudi Medical Journal
|November 21, 2013
Summary
Crohn
Area of Science:
- Gastroenterology and Epidemiology
Background:
- Crohn's disease (CD) prevalence is increasing globally, particularly in previously low-incidence regions like Asia.
- Understanding the epidemiology and risk factors of CD in the Kingdom of Saudi Arabia (KSA) is crucial due to rising incidence.
Purpose of the Study:
- To systematically review the epidemiology and risk factors of Crohn's disease (CD).
- To specifically examine the emergence and characteristics of CD within the Kingdom of Saudi Arabia (KSA).
Main Methods:
- Systematic review of population-based, epidemiological, and clinical character studies on Crohn's disease.
- Data collection focused on prevalence, demographics, and potential etiological factors relevant to KSA.
Main Results:
- Crohn's disease prevalence has significantly increased in KSA over the past three decades.
- Combined ileal and colonic involvement is the most common presentation of CD in KSA.
- Westernization of lifestyle and smoking are identified as probable major contributing factors to CD pathogenesis.
Conclusions:
- There is clear evidence of emerging Crohn's disease in Asia, including KSA.
- Lifestyle changes and smoking are key factors in the rising CD rates.
- Further genetic studies are recommended to elucidate CD etiology in KSA.
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