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Menetrier`s disease in a Saudi child
Fahad A Alfares1, Emad M Raddaoui, Mohammad I El-Mouzan
1Department of Pediatrics, College of Medicine, King Saud University, Riyadh, Kingdom of Saudi Arabia.
Saudi Medical Journal
|November 21, 2013
Summary
Menetrier`s disease, a rare gastric disorder, is exceptionally uncommon in children. This case report details a 5-year-old boy with Menetrier`s disease and concurrent cytomegalovirus infection.
Area of Science:
- Gastroenterology
- Pediatric Pathology
- Infectious Diseases
Background:
- Menetrier`s disease is a rare acquired gastropathy characterized by enlarged gastric folds.
- It typically affects adults, presenting with abdominal pain, vomiting, and hypoalbuminemia.
- Diagnosis relies on clinical, endoscopic, and histopathological findings.
Observation:
- A 5-year-old boy from Saudi Arabia presented with symptoms consistent with Menetrier`s disease.
- Endoscopic examination revealed giant gastric mucosal folds.
- Gastric biopsy showed foveolar hyperplasia and reduced oxyntic glands.
Findings:
- The patient exhibited typical clinical and pathological features of Menetrier`s disease.
- Serological tests confirmed acute cytomegalovirus (CMV) infection.
- This suggests a potential association between CMV infection and Menetrier`s disease in pediatric cases.
Implications:
- This case highlights the possibility of Menetrier`s disease in children presenting with characteristic symptoms.
- The concurrent CMV infection suggests a potential trigger or contributing factor in pediatric Menetrier`s disease.
- Further research may elucidate the role of viral infections in the pathogenesis of this rare condition.
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