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Menetrier`s disease in a Saudi child.

Fahad A Alfares1, Emad M Raddaoui, Mohammad I El-Mouzan

  • 1Department of Pediatrics, College of Medicine, King Saud University, Riyadh, Kingdom of Saudi Arabia.

Saudi Medical Journal
|November 21, 2013
PubMed
Summary

Menetrier`s disease, a rare gastric disorder, is exceptionally uncommon in children. This case report details a 5-year-old boy with Menetrier`s disease and concurrent cytomegalovirus infection.

Area of Science:

  • Gastroenterology
  • Pediatric Pathology
  • Infectious Diseases

Background:

  • Menetrier`s disease is a rare acquired gastropathy characterized by enlarged gastric folds.
  • It typically affects adults, presenting with abdominal pain, vomiting, and hypoalbuminemia.
  • Diagnosis relies on clinical, endoscopic, and histopathological findings.

Observation:

  • A 5-year-old boy from Saudi Arabia presented with symptoms consistent with Menetrier`s disease.
  • Endoscopic examination revealed giant gastric mucosal folds.
  • Gastric biopsy showed foveolar hyperplasia and reduced oxyntic glands.

Findings:

  • The patient exhibited typical clinical and pathological features of Menetrier`s disease.
  • Serological tests confirmed acute cytomegalovirus (CMV) infection.

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  • This suggests a potential association between CMV infection and Menetrier`s disease in pediatric cases.

    • Implications:

    • This case highlights the possibility of Menetrier`s disease in children presenting with characteristic symptoms.
    • The concurrent CMV infection suggests a potential trigger or contributing factor in pediatric Menetrier`s disease.
    • Further research may elucidate the role of viral infections in the pathogenesis of this rare condition.