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Related Concept Videos

Pericarditis I: Introduction01:22

Pericarditis I: Introduction

762
Pericarditis is defined as the inflammation of the pericardium, the thin, sac-like membrane surrounding the heart. This condition can cause significant chest pain and other symptoms, often necessitating medical intervention. The pericardium has two layers: the inner visceral layer and the outer parietal layer, separated by a small amount of fluid that reduces friction during heartbeats.Types of PericarditisPericarditis can be classified into several types based on the duration and nature of the...
762
Pericarditis II: Clinical Features and Diagnostic Tests01:19

Pericarditis II: Clinical Features and Diagnostic Tests

636
Pericarditis is distinguished by inflammation of the pericardium, the fibrous sac that encases the heart. It can be acute, lasting less than six weeks, or chronic, persisting for over three months. Understanding its clinical manifestations and diagnostic findings is crucial for timely and effective management.Clinical ManifestationsWhile pericarditis can be asymptomatic, it usually presents with characteristic symptoms such as:Chest Pain: The most characteristic symptom of pericarditis is chest...
636
Pericarditis III: Medical Management01:17

Pericarditis III: Medical Management

592
The primary objectives of managing pericarditis are to determine the underlying cause, provide effective therapy for treatment and symptom relief, and promptly detect signs and symptoms of cardiac tamponade. The following outlines the essential aspects of medical management for pericarditis:ObjectivesDetermine the Cause: Identifying the underlying cause of pericarditis is crucial for targeted treatment. Causes include viral infections, autoimmune diseases, post-cardiac injury syndrome, and...
592
Pericarditis IV: Nursing Management01:25

Pericarditis IV: Nursing Management

643
Pericarditis, an inflammation of the pericardium, necessitates diligent nursing management to ensure effective patient care and recovery. The initial step in managing pericarditis is a comprehensive patient medical assessment.The patient reports chest pain aggravated by breathing, coughing, and swallowing, which worsens when lying supine. The pain often improves when sitting up and leaning forward. Additional symptoms may include fever, malaise, and, in severe cases, signs of heart failure.
643
Chronic Inflammation: Introduction01:12

Chronic Inflammation: Introduction

50
Chronic inflammation is a prolonged, dysregulated immune response that persists for weeks to years when the inciting stimulus is difficult to eradicate or when self‑antigens drive ongoing reactivity. Morphologically, it is defined by mononuclear cell infiltration, progressive tissue destruction, and concurrent attempts at healing via angiogenesis and fibrosis. Compared with acute inflammation, edema is less prominent while cellular infiltration predominates; triggers include persistent...
50
Chronic Pancreatitis I: Introduction01:24

Chronic Pancreatitis I: Introduction

918
The pancreas, an elongated and flat gland situated behind the stomach, serves a vital function in digesting food and managing blood sugar levels.
Pancreatitis is the inflammation of the pancreas, which occurs when the immune system becomes active and causes swelling, pain, and disruptions in organ function. Pancreatitis can manifest as either an acute or chronic condition.
Acute pancreatitis arises suddenly and lasts for a brief duration, while chronic pancreatitis is a long-term affliction...
918

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[Diagnosis and treatment of ANCA-associated vasculitis : S3 guideline of the German Society for Rheumatology and Clinical Immunology e. V. (DGRh) and German Society for Internal Medicine e. V. (DGIM), German Society for Nephrology e. V. (DGfN), German Society for ENT Medicine and Head and Neck Surgery e. V. (DGHNO-KHC), German Ophthalmological Society e. V. (DOG), German Society for Neurology e. V. (DGN), German Society for Pneumology and Respiratory Medicine e. V. (DGP), German Society for Pathology e. V. (DGP), German Radiological Society, Society for Medical Radiology e. V. (DRG), Federal Association of German Pathologists, Federal Kidney Association e. V., German Rheumatism League Federal Association e. V.]

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Orthotopic Aortic Transplantation: A Rat Model to Study the Development of Chronic Vasculopathy
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[Chronic periaortitis].

J H Schirmer1, M Both, F Moosig

  • 1Klinik für Rheumatologie und Immunologie, Klinikum Bad Bramstedt und Universitätsklinikum Schleswig-Holstein, Oskar-Alexander-Str. 26, 24576, Bad Bramstedt, Deutschland, j.schirmer@klinikumbb.de.

Der Internist
|November 21, 2013
PubMed
Summary
This summary is machine-generated.

Chronic periaortitis is a fibrosing inflammatory disease causing aortic aneurysms and ureter obstruction. Treatment involves steroids, with potential need for immunosuppressants in refractory cases.

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Area of Science:

  • Vascular inflammation
  • Fibrotic diseases
  • Abdominal aortic aneurysms

Context:

  • Chronic periaortitis involves periaortic fibrosis and aneurysm formation, primarily in the retroperitoneum.
  • It can present with systemic inflammation and mechanical complications like ureter obstruction.
  • Diagnosis relies on contrast-enhanced CT or MRI, often requiring biopsy for atypical cases.

Purpose:

  • To outline the characteristics, diagnosis, and management of chronic periaortitis.
  • To highlight the role of imaging and biopsy in diagnosis.
  • To discuss current treatment strategies and areas for future research.

Summary:

  • Chronic periaortitis is characterized by periaortitis, fibrosis, and aortic aneurysms, potentially affecting large vessels.
  • Diagnosis involves advanced imaging (CT/MRI) and biopsy if needed, after excluding secondary causes.
  • Initial treatment includes steroids, with immunosuppressants for refractory cases; complications may require intervention.

Impact:

  • Provides a comprehensive overview of chronic periaortitis for clinicians.
  • Emphasizes the need for further research into optimal immunosuppressive therapy.
  • Guides diagnostic and therapeutic approaches for this rare condition.