Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Halide concentrations in camel plasma in various states of hydration.

Biological trace element research·2013

Same author

The effect of β-adrenoceptor blockade on body temperature and plasma renin activity in heat-exposed man.

British journal of clinical pharmacology·2012

Same author

Serum amyloid A: an early and accurate marker of neonatal early-onset sepsis.

Journal of perinatology : official journal of the California Perinatal Association·2007

Same author

Reactions of peripheral blood mononuclear cells (PBMC) of camels with monoclonal antibodies against ruminant leukocytes.

Comparative immunology, microbiology and infectious diseases·2002

Same author

Detection of subclinical mastitis in dromedary camels (Camelus dromedarius) using somatic cell counts and the N-acetyl-beta-D-glucosaminidase test.

Tropical animal health and production·2002

Same author

Evidence for exercise-induced bone formation in premature infants.

International journal of sports medicine·2002

Search research articles

Related Experiment Video

Updated: May 5, 2026

18F-Labeling of Radiotracers Functionalized with a Silicon Fluoride Acceptor SiFA for Positron Emission Tomography

18F-Labeling of Radiotracers Functionalized with a Silicon Fluoride Acceptor SiFA for Positron Emission Tomography

Published on: January 11, 2020

Distribution of(31)Silicon-Labeled silicic acid in the rat.

G M Berlyne¹, R Shainkin-Kestenbaum, R Yagil

¹Department of Medicine, Downstate Medical Center and Brooklyn VA Medical Center, Brooklyn, New York, NY.

Biological Trace Element Research

|November 21, 2013

Summary

This study tracked silicon-31 (31Si) distribution in rats, finding highest concentrations in kidneys and skin. Further research is needed to understand silicon metabolism in key organs like the kidneys, skin, bone, and brain.

More Related Videos

Establishing a Silicosis Rat Model via Exposure of Whole-Body to Respirable Silica

Establishing a Silicosis Rat Model via Exposure of Whole-Body to Respirable Silica

Published on: October 28, 2022

A Dual Tracer PET-MRI Protocol for the Quantitative Measure of Regional Brain Energy Substrates Uptake in the Rat

A Dual Tracer PET-MRI Protocol for the Quantitative Measure of Regional Brain Energy Substrates Uptake in the Rat

Published on: December 28, 2013

Related Experiment Videos

Last Updated: May 5, 2026

18F-Labeling of Radiotracers Functionalized with a Silicon Fluoride Acceptor SiFA for Positron Emission Tomography

18F-Labeling of Radiotracers Functionalized with a Silicon Fluoride Acceptor SiFA for Positron Emission Tomography

Published on: January 11, 2020

Establishing a Silicosis Rat Model via Exposure of Whole-Body to Respirable Silica

Establishing a Silicosis Rat Model via Exposure of Whole-Body to Respirable Silica

Published on: October 28, 2022

A Dual Tracer PET-MRI Protocol for the Quantitative Measure of Regional Brain Energy Substrates Uptake in the Rat

A Dual Tracer PET-MRI Protocol for the Quantitative Measure of Regional Brain Energy Substrates Uptake in the Rat

Published on: December 28, 2013

Area of Science:

Biochemistry
Radiochemistry
Toxicology

Background:

Silicon is an essential trace element with incompletely understood metabolic pathways.
Understanding silicon distribution is crucial for assessing its biological roles and potential toxicity.

Purpose of the Study:

To investigate the organ and tissue distribution of silicon-31 (31Si)-labeled silicic acid in a mammalian model.
To identify key organs and tissues involved in silicon uptake and retention.

Main Methods:

Carrier-free 31Si was prepared via neutron activation.
31Si-labeled silicic acid was administered to five male albino rats.
Organ and tissue distribution was quantified 30 minutes post-injection.

Main Results:

Kidneys showed the highest concentration (0.85% ID/g), followed by skin (0.3% ID/g).
Voluntary muscle contained the largest percentage of injected dose per organ (14.6% ID/organ).
Significant silicon accumulation was also observed in skin, bone, liver, testes, and brain.

Conclusions:

The distribution pattern suggests specific uptake mechanisms in organs like the kidney and skin.
Further research into silicon metabolism is warranted, particularly concerning its role in kidney, skin, bone, and brain tissues.
These findings provide a foundation for future studies on silicon's physiological and pathological significance.