Related Experiment Video
Updated: May 5, 2026

A Precision Medicine Tool for Measurement and Monitoring of Hemoglobin S in Sickle Cell Disease Patients Receiving Transfusion Therapy
Serum copper and zinc values compared with serum iron, total iron-binding capacity, and transferrin saturation in
O Donma1, G Yüregir, M M Donma
1Medical Faculty, Biochemistry Department, Cukurova University, Adana, Turkey.
Abstract:
Reliable data for the trace element values of the biological systems in some diseases are still very rare. Sickle cell trait is one of them.For this purpose, serum iron, zinc, and copper values, together with the total iron binding capacity and saturation percent, were determined in cases with sickle cell trait, eliminating all the sources contributing to deviations from the normal values by choosing a control group from the relatives of the cases.In this study, the values of two groups were compared on the basis of the difference in hemoglobin type, which was the only parameter affecting the trace element analysis.

