Thromboelastographic Study of Psychophysiological Stress: A Review

Area of Science:

• Hemostasis research
• Coagulation cascade analysis
• Fibrinolysis studies

Background:

• Thromboelastography (TEG) is increasingly utilized in hemostasis research.
• TEG evaluates the complete blood coagulation process, from initiation to clot dissolution.
• Its application extends to assessing the impact of psychological and physiological stressors on coagulation.

Purpose of the Study:

• To conduct a comprehensive review of Thromboelastography applications in stress assessment.
• To analyze the diverse methodologies and settings employed in TEG studies of stress.
• To discuss the author's contributions and future research directions in this field.

Main Methods:

• Comprehensive literature review of Thromboelastography studies.
• Analysis of various stressor types (physical, emotional) and their effects on coagulation.
• Examination of methodological variations in TEG (instrumentation, blood type, activation methods, study settings).

Main Results:

• Thromboelastography is predominantly used to investigate the effects of physiological stress.
• The review highlights the unique methodological aspects of TEG in different study designs.
• Diverse stressors, including exercise and emotional challenges, have been evaluated using TEG.

Conclusions:

• TEG is a valuable tool for understanding hemostasis under various forms of stress.
• Future development of TEG can enhance the evaluation of hemostatic responses and stress-related pathologies.
• This review provides a foundation for further research into TEG's role in stress physiology.