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Related Experiment Video

Updated: May 5, 2026

Non-invasive Optical Measurement of Cerebral Metabolism and Hemodynamics in Infants
11:39

Non-invasive Optical Measurement of Cerebral Metabolism and Hemodynamics in Infants

Published on: March 14, 2013

21.2K

Testing a novel method for measuring sleeping metabolic rate in neonates.

Suzanne S Summer1, Jesse M Pratt2, Elizabeth A Koch3

  • 1Clinical Translational Research Center suzanne.summer@cchmc.org.

Respiratory Care
|November 21, 2013
PubMed
Summary

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A smaller hood for indirect calorimetry (IC) accurately measures sleeping metabolic rate (SMR) in healthy infants. This smaller hood may also improve SMR testing for neonates with congenital heart disease.

Area of Science:

  • Neonatology
  • Pediatric critical care
  • Metabolic research

Background:

  • Sleeping metabolic rate (SMR) is a proxy for basal metabolic rate in infants.
  • Indirect calorimetry (IC) measures SMR to assess feeding adequacy in neonates.
  • Standard IC hoods are not suitable for small infants.

Purpose of the Study:

  • To compare SMR measurements in neonates using a standard large hood versus a nonstandard smaller hood.
  • To evaluate the feasibility of using a smaller hood for SMR assessment in neonates.

Main Methods:

  • SMR was measured in healthy neonates and those with single-ventricle congenital heart disease using both small and large hoods.
  • Minute ventilation (V̇E) and fraction of exhaled carbon dioxide (FĒCO2) were measured to assess data quality.
Keywords:
basal metabolic rateenergy metabolismindirect calorimetryinfantnewborn

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Related Experiment Videos

Last Updated: May 5, 2026

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  • Spearman's correlations assessed the association between SMR measurements from both hoods.

    • Main Results:

    • SMR measurements were similar between small and large hoods in healthy neonates.
    • In neonates with congenital heart disease, SMR was significantly higher with the small hood compared to the large hood.
    • Fraction of exhaled carbon dioxide (FĒCO2) was higher with the small hood in both groups.

    Conclusions:

    • A smaller IC hood provides comparable SMR measurements to a standard large hood in healthy neonates.
    • The smaller hood may enhance SMR testing in compromised neonates, such as those with congenital heart disease.
    • Testing time and procedure were not negatively affected by the smaller hood size.