Related Experiment Video
Updated: May 5, 2026

In Vivo Morphometric Analysis of Human Cranial Nerves Using Magnetic Resonance Imaging in Menière's Disease Ears and Normal Hearing Ears
Published on: February 21, 2018
Morphological MRI and 3D Myelocisternography MRI in Spontaneous Intracranial Hypotension. A Report of Four Cases
F A Lupo1, A Paladini, G Sticchi
1Neuroradiology Unit, Lecce Health Trust, "V. Fazzi" Hospital; Lecce, Italy - fa_lupo@tin.it.
Abstract:
Spontaneous intracranial hypotension (SIH) is a polyhedric syndrome whose common denominator is postural headache. We describe four cases of spontaneous intracranial hypotension, their clinical-iconographic aspects, and emphasize the use of morphological MRI in the diagnosis and follow-up of this condition. In addition, we propose 3D myelocisternography MRI as a further contribution in cerebrospinal fluid losses causing postural headache.
Insights
Spontaneous intracranial hypotension causes postural headaches. Morphological MRI aids diagnosis and follow-up, with 3D myelocisternography offering further insights into cerebrospinal fluid loss.
Area of Science:
- Neurology
- Radiology
- Neurosurgery
Background:
- Spontaneous intracranial hypotension (SIH) is a complex syndrome characterized by postural headache.
- Cerebrospinal fluid (CSF) loss is the underlying cause of SIH.
- Accurate diagnosis and monitoring are crucial for effective patient management.
Purpose of the Study:
- To present four cases of SIH, detailing their clinical and imaging features.
- To highlight the diagnostic and follow-up utility of morphological Magnetic Resonance Imaging (MRI).
- To explore the role of 3D myelocisternography MRI in identifying CSF leaks.
Main Methods:
- Case series presentation of four patients diagnosed with SIH.
- Detailed analysis of clinical presentations and symptoms.
- Utilized morphological MRI for diagnosis and monitoring.
- Employed 3D myelocisternography MRI to investigate CSF loss.
Main Results:
- All four patients presented with characteristic postural headaches.
- Morphological MRI effectively visualized signs of intracranial hypotension.
- 3D myelocisternography MRI provided additional details on CSF leakage points.
- Consistent correlation between imaging findings and clinical symptoms was observed.
Conclusions:
- Morphological MRI is a valuable tool for diagnosing and managing SIH.
- 3D myelocisternography MRI enhances the detection of CSF leaks in SIH.
- Comprehensive imaging, including advanced MRI techniques, is essential for understanding and treating SIH.
Related Concept Videos
Imaging Studies for Cardiovascular System IV: CMRI
Increased Intracranial Pressure l: Introduction

