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Vision loss after accidental methanol intoxication: a case report.

Marilita M Moschos1, Nikolaos S Gouliopoulos, Alexandros Rouvas

  • 11st Department of Ophthalmology, University of Athens Medical School, 'G, Genimmatas' General Hospital Athens, 154 Mesogion Avenue, Holargos 11527, Athens, Greece. moschosmarilita@yahoo.fr.

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|November 22, 2013
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Summary
This summary is machine-generated.

Methanol intoxication caused irreversible blindness in a patient, confirmed by optical coherence tomography and electrophysiological tests. This case highlights severe visual consequences of accidental methanol ingestion.

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Area of Science:

  • Ophthalmology
  • Toxicology

Background:

  • Methanol intoxication is a severe condition with potential for permanent visual impairment, neurological dysfunction, and death.
  • Accidental ingestion of methanol-containing substances can lead to critical health outcomes.

Observation:

  • A 49-year-old man experienced bilateral irreversible blindness after accidental methanol ingestion.
  • Ophthalmological examination revealed no light perception, unreactive pupils, and normal retina, but pathological visual evoked potentials and optical coherence tomography of the optic nerve heads.

Findings:

  • This case report is the first to document anatomical and functional abnormalities in methanol intoxication using optical coherence tomography and electrophysiological tests.
  • Electrophysiological tests and optical coherence tomography showed pathological changes in the optic nerve heads, despite a normal electroretinogram.

Implications:

  • The findings suggest methanol toxicity affects photoreceptors, Müller cells, and the retrolaminar optic nerve.
  • This case underscores the critical need for prompt diagnosis and management of methanol intoxication to prevent irreversible visual loss.