Related Experiment Video
Updated: May 5, 2026

07:23
Detection of Infectious Virus from Field-collected Mosquitoes by Vero Cell Culture Assay
Published on: June 9, 2011
17.9K
Tick-borne encephalitis in Bulgaria, 2009 to 2012.
E Mohareb1, I Christova, A Soliman
1United States Naval Medical Research Unit-3, Cairo, Egypt.
Summary
Three cases of tick-borne encephalitis (TBE) were confirmed in Bulgaria between 2009 and 2012, marking the first reported instances. Increased TBE awareness among medical professionals is crucial for accurate diagnosis and patient care.
Area of Science:
- Infectious Diseases
- Virology
- Public Health
Background:
- Tick-borne encephalitis (TBE) incidence has significantly risen across Europe.
- Bulgaria has historically reported very few TBE cases over the past 60 years.
Observation:
- A study investigated TBE in 86 patients hospitalized with viral meningitis of unknown cause in Bulgaria from 2009 to 2012.
- Three patients were diagnosed with acute TBE during this period.
Findings:
- This study identified the first confirmed cases of TBE in Bulgaria.
- The confirmed TBE cases occurred in 2009 and 2012.
Implications:
- The findings suggest TBE risk may be underestimated in Bulgaria.
- Low TBE awareness among healthcare providers likely contributes to underdiagnosis.
Related Concept Videos
Arboviral Encephalitis
70
Arboviral encephalitis refers to brain inflammation caused by arthropod-borne viruses, particularly those transmitted through mosquito vectors. Among these, West Nile virus (WNV), a member of the Flaviviridae family, is a significant public health concern. WNV is an enveloped, positive-sense, single-stranded RNA virus. Human infection typically begins when an infected mosquito introduces the virus into the dermis during feeding. The primary transmission cycle involves birds as amplifying hosts...
70
Encephalitis l: Introduction
27
Encephalitis is inflammation of the brain parenchyma, most often due to infections or autoimmune processes. It presents with neuropsychiatric features such as fever, altered mental status, behavioral changes, cognitive dysfunction, seizures, focal deficits, and sometimes autonomic instability. In some cases, the meninges are also involved, resulting in meningoencephalitis.Infectious CausesInfectious encephalitis is most commonly viral but can also result from bacterial, fungal, or parasitic...
27
Encephalitis ll: Pathophysiology
30
Encephalitis is inflammation of the brain parenchyma caused by direct viral invasion or immune-mediated mechanisms triggered by infections or tumors. Both processes lead to neuronal injury, disrupted neurotransmission, and diverse neurological symptoms, often with overlapping clinical and pathological features.Autoimmune EncephalitisIn autoimmune encephalitis, antibodies target neuronal antigens on cell surfaces, synapses, or within neurons. A key example is anti-NMDAR encephalitis, which can...
30
Viral Meningitis
217
Viral meningitis is the most common form of meningitis and is often referred to as aseptic meningitis to indicate the absence of bacterial involvement. It is generally milder than bacterial meningitis, with symptoms including fever, headache, stiff neck, drowsiness, nausea, photophobia, and vomiting. Rarely, more severe manifestations or death may occur. Common causative agents include enteroviruses, particularly coxsackie A and B viruses and echoviruses, all members of the Enterovirus genus...
217

