Related Experiment Video
Updated: May 5, 2026

Efficient Sampling of Genetically Encoded Biosensor Design Space Enabled with a Design of Experiments and Automation Workflow
Published on: October 17, 2025
The use of simple kinetic models to help design environmental monitoring systems
G B Wiersma1, C W Frank, M J Case
1EG & G Idaho, Inc., P.O. Box 1625, 83415, Idaho Falls, ID, USA.
Abstract:
This paper describes the application of simple linear models to help design environmental monitoring systems. This process involves five steps: (1) The derivation of a schematic of the identified pollutant's transport and fate. (2) The derivation of the equation in the schematic. (3) Estimation of input data and numerical solution. (4) Comparison with initial field data. (5) Design of a monitoring system.Two examples of how this system was applied under field conditions are given. Advantages of this approach are: (1) It forces a consideration of the system as a whole rather than a series of distinct environmental components. (2) It forces a consideration of the physical-chemical and biological factors effecting pollutant transport in the system. (3) It sets up an analytical procedure for data analysis at the time the monitoring system is designed. (4) It helps show the functional relationship between pollutant levels in different environmental media. (5) It identifies points where sampling design could be changed to provide for a more efficient monitoring system. (6) It identifies gaps in our knowledge base.
More Related Videos
10:37Procedure to Evaluate the Efficiency of Flocculants for the Removal of Dispersed Particles from Plant Extracts
Published on: April 9, 2016
20:24Characterization of Complex Systems Using the Design of Experiments Approach: Transient Protein Expression in Tobacco as a Case Study
Published on: January 31, 2014
Related Concept Videos
Mechanistic Models: Compartment Models in Individual and Population Analysis
Typical Model Studies
Pharmacokinetic Models: Comparison and Selection Criterion
Physiological models take a detailed approach by considering specific molecular processes. They can predict drug distribution, metabolism, and elimination changes, providing a comprehensive understanding of how drugs interact with the body.
Pharmacokinetic Models: Overview
There are three primary types of models: empirical, compartment, and physiological. Empirical models, with minimal...
Methods of Medium Optimization
Mechanistic Models: Overview of Compartment Models