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Drug Dosing: Geriatric Patients01:15

Drug Dosing: Geriatric Patients

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Elderly individuals encompass a diverse population with varying degrees of age-related physiological changes. Defining the elderly presents challenges, as the geriatric population is often arbitrarily categorized as individuals older than 65. However, many individuals in this group lead active and healthy lives, with an increasing number surpassing 85 years and falling into the older elderly category. Physiological changes associated with aging impact performance capacity and homeostatic...
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Pharmacodynamics in Geriatric Patients: Effects of Age01:27

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Age-related pharmacokinetic changes are extensively documented, but understanding age-related pharmacodynamic alterations is relatively limited. This knowledge gap can be partly attributed to the complexity of developing appropriate measures of drug responses compared to bioanalytical methods for determining drug concentrations.Most information regarding age-related differences in human pharmacodynamics originates from cross-sectional studies. However, these studies assume that observed mean...
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Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Distribution01:00

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Drug distribution in the human body is influenced by several factors, including plasma protein concentration, body composition, blood flow, tissue-protein concentration, and tissue fluid pH. Among these, changes in plasma protein concentration and body composition due to aging significantly affect how drugs are distributed within the body. Specifically, aging is associated with a decrease in albumin levels by about 10% and an increase in α1-acid glycoprotein levels. These alterations are...
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Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Metabolism01:18

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Geriatric patients show significant variation in how their bodies process medications, which can change how effective and safe treatments are. The liver is the primary organ where drug metabolism occurs, involving two main types of chemical reactions: phase I and II. Phase I metabolism is driven by the cytochrome P450 enzyme system, which includes key types such as CYP3A, CYP2D6, and CYP2C9. Research indicates that while aging doesn't notably alter the levels or activity of these enzymes, it...
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Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Absorption01:22

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As individuals age, their body's physiology evolves, affecting drug pharmacokinetics. The most apparent changes occur in the gastrointestinal tract, where an increase in gastric pH, a delay in gastric emptying, and a reduction in gastrointestinal motility are observed. Remarkably, these changes do not substantially modify the absorption of orally administered drugs, particularly those absorbed via passive diffusion.Transdermal drug delivery emerges as a highly viable method for older adults due...
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The Effect of Aging on Tissues01:19

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Several body functions deteriorate with age. The external signs of aging are easily identifiable. For example, the skin becomes dry, less elastic, and thins out, forming wrinkles. The skin of the face begins to appear looser due to a decrease in the levels of elastic and collagen fibers in the connective tissue. Additionally, melanin production in the hair follicle decreases with age, resulting in gray hair. Moreover, the senses of sight and hearing decline, so glasses and hearing aids may...
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Updated: May 5, 2026

Oral Health Assessment by Lay Personnel for Older Adults
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Nutritional risk among older Canadians.

Pamela L Ramage-Morin1, Didier Garriguet

  • 1Health Analysis Division, Statistics Canada, Ottawa, Ontario, K1A 0T6. Pamela.Ramage-Morin@statcan.gc.ca

Health Reports
|November 22, 2013
PubMed
Summary
This summary is machine-generated.

A significant portion of Canadian seniors face nutritional risk. Factors like depression, disability, and social isolation increase this risk, highlighting the need for targeted interventions in community settings.

Keywords:
dieteatingfood intakemalnutritionmorbiditynutrition assessmentseniors

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Area of Science:

  • Gerontology
  • Public Health Nutrition
  • Epidemiology

Background:

  • Nutritional risk screening is crucial for identifying malnutrition.
  • This study provides the first population-level assessment of nutritional risk in Canadian seniors.
  • Focuses on community-dwelling older adults aged 65+.

Purpose of the Study:

  • To assess the prevalence of nutritional risk among Canadian seniors.
  • To identify factors associated with nutritional risk in this demographic.
  • To report on the distribution of responses using the SCREEN II-AB tool.

Main Methods:

  • Utilized data from the 2008/2009 Canadian Community Health Survey-Healthy Aging.
  • Employed logistic regression models to examine associated factors.
  • Analyzed nutritional risk using the SCREEN II-AB instrument.

Main Results:

  • 34% of Canadian seniors (65+) were identified as being at nutritional risk.
  • Higher risk observed in women, individuals with depression, disability, poor oral health, and those living alone.
  • Low social support, infrequent social participation, and not driving were also associated with increased risk.

Conclusions:

  • Nutritional risk is prevalent among community-dwelling seniors in Canada.
  • Specific characteristics identify high-risk individuals, informing targeted screening strategies.
  • Evidence supports the need for proactive nutritional assessment in older populations.