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Related Concept Videos

Disorders of the Nervous Tissue01:28

Disorders of the Nervous Tissue

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Nervous tissue is a vital component of the human body's communication system, enabling us to perceive and respond to stimuli. However, like all other tissues, it is vulnerable to disorders and diseases that can significantly impact our neurological functioning.
Homeostatic Imbalances:
Alzheimer's disease manifests as a gradual decline in memory and cognitive abilities, attributed to the buildup of amyloid plaques and neurofibrillary tangles in the brain.
Parkinson's disease arises from the...
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Nervous Tissue: Glial Cells01:31

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Glia, or neuroglia, are vital support cells that assist neurons in their functions. The term "glia" originates from the Greek word for "glue," reflecting their role in holding the nervous system together. These cells can be categorized into six types: four in the central nervous system (CNS) and two in the peripheral nervous system (PNS).
The CNS glial cell includes the astrocytes, the oligodendrocytes, the microglia, and the ependymal cells.
Astrocytes are star-shaped glial...
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Neural Regulation01:37

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Digestion begins with a cephalic phase that prepares the digestive system to receive food. When our brain processes visual or olfactory information about food, it triggers impulses in the cranial nerves innervating the salivary glands and stomach to prepare for food.
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The Retinoblastoma Gene01:20

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Tumor suppressor genes are normal genes that can slow down cell division, repair DNA mistakes, or program the cells for apoptosis in case of irreparable damage. Hence, they play an essential role in preventing the proliferation of damaged cells.
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Nervous Tissue: Myelin01:25

Nervous Tissue: Myelin

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The myelin sheath is a multilayered lipid and protein covering that insulates the axon of a neuron, enhancing the speed of nerve impulse conduction. Axons without this sheath are referred to as unmyelinated. Two types of neuroglia, Schwann cells in the peripheral nervous system (PNS) and oligodendrocytes in the central nervous system (CNS) are responsible for producing myelin sheaths.
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Peripheral Nervous System: Ganglia and Nerves01:24

Peripheral Nervous System: Ganglia and Nerves

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The Peripheral Nervous System (PNS) is a crucial component of the body's neural network, extending beyond the central nervous system (CNS) to bridge the gap between the CNS and the external environment. It encompasses nerves, ganglia, and sensory receptors.
Nerves
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Updated: May 5, 2026

An Orthotopic Sciatic Nerve Xenograft for Neurofibromatosis Type 1 Neurofibromas
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[Neurofibromatoses].

A Zimmer1

  • 1Klinik für Diagnostische und Interventionelle Neuroradiologie, Universitätsklinikum des Saarlandes, Kirrberger Straße, 66421, Homburg/Saar, Deutschland, anna.zimmer@uks.eu.

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Neurofibromatosis type 1 (NF1) and type 2 (NF2) are distinct genetic disorders causing tumors. This review details their diagnosis, imaging, and prognosis.

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Area of Science:

  • Genetics and rare diseases
  • Neurocutaneous disorders
  • Oncology

Context:

  • Neurofibromatosis type 1 (NF1) and type 2 (NF2) are distinct autosomal dominant hereditary neurocutaneous disorders.
  • These phacomatoses involve tumors of the peripheral nerve sheath and schwannomatosis.
  • Understanding their unique clinical and genetic profiles is crucial.

Purpose:

  • To differentiate between NF1 and NF2 based on clinical and genetic aspects.
  • To present characteristic imaging findings for diagnosis and follow-up.
  • To assess the prognostic role of imaging in these multisystemic disorders.

Summary:

  • NF1 and NF2 are distinct hereditary neurocutaneous disorders.
  • Review covers clinical presentation, diagnostic criteria, and characteristic imaging findings.
  • Emphasizes imaging's role in diagnosis, follow-up, and prognosis.

Impact:

  • Provides a comprehensive overview for clinicians and researchers.
  • Aids in accurate diagnosis and management of NF1 and NF2.
  • Highlights the importance of advanced imaging in patient care.