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Updated: May 5, 2026

Biosynthesis of a Flavonol from a Flavanone by Establishing a One-pot Bienzymatic Cascade
Published on: August 14, 2019
Enzymic synthesis of γ-coniceine in Conium maculatum chloroplasts and mitochondria
1Department of Pharmacognosy, The School of Pharmacy, London University, 29-39, Brunswick Square, WC1N 1AX, London, UK.
Abstract:
Further studies of the transaminase responsible for the first committed step in alkaloid formation in Conium maculatum have shown the L-alanine: 5-ketooctanal transaminase to occur in both the mitochondria and chloroplast. Experiments suggest that these enzymes are the isoenzymes Transaminase A and B respectively previously isolated by the author. It is suggested that the chloroplast enzyme is normally responsible for alkaloid production.
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