Correlation between microalbuminuria and cardiovascular events.
Yakun Wang1, Aihong Yuan, Chen Yu
1Department of Nephrology, Tongji Hospital of Tongji University Shanghai, 200065.
International Journal of Clinical and Experimental Medicine
|November 22, 2013
Summary
Microalbuminuria (MAU) is a significant risk factor for major cardiovascular events and heart failure. Early treatment of MAU is crucial for reducing cardiovascular disease incidence and progression.
Area of Science:
- Nephrology
- Cardiology
- Internal Medicine
Background:
- Microalbuminuria (MAU) is a marker of kidney damage.
- MAU is associated with increased cardiovascular risk.
Purpose of the Study:
- To investigate the relationship between microalbuminuria and cardiovascular events.
- To determine if MAU is an independent risk factor for cardiovascular events.
Main Methods:
- 1259 hospitalized patients underwent urinary albumin detection.
- Patients were categorized into normal albuminuria (NAU) and microalbuminuria (MAU) groups.
- Demographic data and cardiovascular events were collected and analyzed.
Main Results:
- The MAU group was older and had a higher prevalence of diabetes and/or hypertension.
- Cardiovascular events and congestive heart failure were significantly more prevalent in the MAU group.
- Logistic regression indicated MAU increased the risk for major cardiovascular events (OR 1.438) and congestive heart failure (OR 2.540).
Conclusions:
- Microalbuminuria significantly increases the risk of major cardiovascular events and congestive heart failure.
- MAU is an independent risk factor for cardiovascular events, irrespective of diabetes or hypertension.
- Timely treatment of MAU (30-300 mg/24 h) can reduce cardiovascular event incidence and delay disease progression.
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