Radiation therapy for secondary cutaneous plasmacytomas
Jerry Liu1, Richard Bakst, Robert Phelps
1Department of Radiation Oncology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
Case Reports in Hematology
|November 22, 2013
Summary
This case report details a rare instance of secondary cutaneous plasmacytomas in a patient with IgA-lambda multiple myeloma. Palliative radiation therapy provided pain relief for these rare skin lesions.
Area of Science:
- Oncology
- Hematology
- Dermatology
Background:
- Multiple myeloma is a plasma cell malignancy.
- Cutaneous involvement is rare, especially secondary plasmacytomas.
- IgA-lambda myeloma is a specific subtype.
Purpose of the Study:
- To report a unique case of secondary cutaneous plasmacytomas in IgA-lambda multiple myeloma.
- To describe the treatment and outcome of palliative radiation for these lesions.
- To highlight the rarity of dermal myeloma involvement.
Main Methods:
- Case report of a 75-year-old male with recurrent IgA-lambda multiple myeloma.
- Description of secondary cutaneous plasmacytomas developing 15 years post-diagnosis.
- Treatment with palliative involved field 3D conformal photon or en face electron therapy concurrently with chemotherapy.
Main Results:
- The patient achieved good to complete response with pain palliation at irradiated sites.
- The skin lesions showed response to palliative radiation.
- The patient survived approximately 7 months after developing skin lesions.
Conclusions:
- Secondary cutaneous plasmacytomas in IgA-lambda multiple myeloma are rare.
- Palliative involved field radiation can be effective for symptom management.
- This case underscores the diverse clinical manifestations of multiple myeloma.
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