Epidemiological situation of toxocariasis in Iran: meta-analysis and systematic review

Toxocariasis is the clinical terms applied to infection of human with ascarid nematodes in the order Ascaridida, named toxocara canis and toxocara cati. It is transmitted from dog and cat to humans. Accidental ingestion of parasite eggs causes ocular and visceral larva migrans in human. The aim of this study is to study epidemiology of toxocariasis in Iran using meta-analysis and systematic review. Using main key words of toxocariasis including epidemiology, Toxocara spp. Iran, dog and cat in databases such as SID, Google scholar, Pubmed, Magiran and Iranmedex, a number of 50 articles was extracted. A number of 27 articles of them were eligible for meta-analysis. Data extracted from articles and archived in excel software for analysis. Variance of each study obtained using binomial distribution. Heterogeny of studies surveyed using Cochrans Q test. Data analyzed using Random Effect Model test. Overall prevalence of toxocariasis obtained 21.6% in Iran. In total of 27 articles, 6911 samples including 1543 carnivores, (13 articles), 4569 human sera (10 articles) and 799 soil samples (4 articles) has been investigated. Seropositivity for human toxocariasis 15.8% (95%CI, 9.2-22.5), soil contamination for Txocara spp. eggs 21.6% (95%CI,-1.6-44.8) and dogs and cats infections with adult worm 26.8% (95%CI, 18.7-36.8) was obtained. Results of this study show that prevalence of toxocariasis has a growing trend in Iran. It could be decreased using education, culture making and giving information to people.