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Computerized venous strain-gauge plethysmography is a reliable method for measuring venous function.

S Rosfors1, L M Persson1, L Blomgren2

  • 1Department of Clinical Physiology, Södersjukhuset, Stockholm, Sweden; Karolinska Institutet, Stockholm, Sweden.

European Journal of Vascular and Endovascular Surgery : the Official Journal of the European Society for Vascular Surgery
|November 23, 2013
PubMed
Summary
This summary is machine-generated.

New reference values for computerized venous strain-gauge plethysmography (SGP) were established in healthy individuals. This method demonstrates high reproducibility and sensitivity for assessing venous disease, with reduced values found in deep venous thrombosis (DVT) limbs.

Keywords:
Chronic venous diseasePost-thrombotic diseaseReference valuesVenous functionVenous plethysmography

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Area of Science:

  • Vascular Medicine
  • Diagnostic Imaging
  • Biomedical Engineering

Background:

  • Computerized strain-gauge plethysmography (SGP) requires established reference values for accurate clinical interpretation.
  • Reproducibility and the influence of demographic factors on SGP variables need thorough investigation.

Purpose of the Study:

  • To establish reference values for computerized SGP in healthy individuals.
  • To assess the reproducibility of computerized SGP.
  • To evaluate the impact of age, gender, BMI, and post-thrombotic syndrome on SGP outcomes.

Main Methods:

  • Sixty-three healthy controls and 56 patients with prior deep venous thrombosis (DVT) were enrolled.
  • Computerized SGP was performed to assess venous outflow capacity, reflux, and muscle pump function.
  • Analysis included comparisons between DVT limbs, contralateral limbs, and healthy controls.

Main Results:

  • All SGP variables were significantly reduced in DVT limbs compared to controls.
  • Outflow capacity measures showed a coefficient of variation (CV) of 5-6%; exercise-induced volume changes had a CV of 10-15%.
  • In symptomatic post-thrombotic limbs, half-refilling time correlated with edema and chronic skin changes.

Conclusions:

  • The study proposes new reference values for computerized SGP derived from healthy controls.
  • The computerized approach ensures high reproducibility.
  • Computerized SGP is a sensitive and useful tool for the quantitative functional assessment of venous disease.