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Idiopathic intracranial hypertension in pediatric population: case series from India
Arun Grace Roy1, Kollencheri Puthenveettil Vinayan, Anand Kumar
1Department of Neurology, Amrita Institute of Medical Sciences, Cochin, Kerala, India.
Insights
Idiopathic intracranial hypertension (IIH) in children presents similarly to adults, with headache being common. Prompt treatment leads to symptom resolution in most pediatric cases, with no recurrence observed over two years.
Area of Science:
- Pediatric Neurology
- Ophthalmology
- Neuroscience
Background:
- Idiopathic intracranial hypertension (IIH) is recognized in adults, but its presentation in children is less frequently reported and can vary by age.
- Understanding pediatric IIH is crucial due to potential variations in clinical presentation.
Purpose of the Study:
- To detail the clinical characteristics, diagnostic investigations, therapeutic interventions, and outcomes of pediatric patients (<18 years) with IIH.
- To contribute to the understanding of IIH in a young population.
Main Methods:
- A retrospective hospital-based study analyzed 25 children diagnosed with IIH using modified Dandy's criteria.
- Data included clinical presentation, investigations, treatment, and a 2-year follow-up period.
Main Results:
- The study included a 4-month-old infant; common symptoms were headache (76%), vomiting (72%), and papilledema (72%).
- Mean cerebrospinal fluid (CSF) pressure was 330 mm H2O. Infants exhibited irritability and bulging fontanelles. 24 patients achieved complete symptom resolution.
- No recurrence was noted during the 2-year follow-up.
Conclusions:
- Idiopathic intracranial hypertension (IIH) can affect individuals of all ages, including infants.
- Clinical features in children resemble adults, with distinct signs in infants. Papilledema absence doesn't rule out IIH.
- CSF pressure monitoring is vital; early treatment prevents long-term deficits.
Background:
Idiopathic intracranial hypertension (IIH) is a well described entity in adults. In pediatric age group the presentation of disease can vary depending on the age of patients and is less frequently reported.
Aim:
The aim of this study is to describe the clinical features, investigations, treatment and outcome of IIH in pediatric population (age <18 years).
Materials And Methods:
This retrospective hospital based study was carried out on 25 children with diagnosis of IIH based on modified Dandys criteria. Their clinical, investigation, treatment, outcome and follow-up for 2 year period were analyzed.
Results:
Out of the 25 children, the youngest child was 4-month-old infant. The commonest symptom was headache (76%) followed by vomiting and papilledema (72%). The mean cerebrospinal fluid (CSF) pressure was 330 mm of H 2 O. In Infants irritability and bulging anterior fontanelle was seen. A total of 24 patients showed a complete resolution of symptom. None of patient had recurrence over a period of 2 years follow-up.
Conclusion:
IIH can present at any age group. This is the largest series of IIH reported in pediatric population in India. The clinical features are similar to adult patients except in infants. Absence of papilledema does not exclude the diagnosis of IIH. CSF pressure monitoring is needed in suspected cases of IIH. Early and prompt treatment can prevent deficits.
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