Systematic use of transradial PCI in patients with ST-segment elevation myocardial infarction: a call to "arms"

Mackram F Eleid1, Charanjit S Rihal, Rajiv Gulati

  • 1Division of Cardiovascular Diseases, Mayo Clinic College of Medicine, Rochester, Minnesota.

Insights

Transradial percutaneous intervention (TRI) is increasingly recommended for ST-segment elevation myocardial infarction (STEMI) patients, offering reduced bleeding and mortality. Wider adoption is encouraged despite historical concerns and slow implementation.

Area of Science:

  • Cardiology
  • Interventional Cardiology
  • Vascular Access

Background:

  • Transradial percutaneous intervention (TRI) is gaining support as a preferred access site for ST-segment elevation myocardial infarction (STEMI).
  • Historically, concerns regarding procedure time, door-to-device time, and operator experience limited TRI use in STEMI.
  • Growing evidence highlights the link between periprocedural bleeding and mortality in acute coronary syndromes, increasing interest in TRI for bleeding reduction.

Purpose of the Study:

  • To review the current evidence supporting transradial percutaneous intervention (TRI) in STEMI patients.
  • To address barriers to TRI adoption and advocate for its increased implementation in STEMI treatment.

Main Methods:

  • Systematic review of registry data, meta-analyses, and randomized control trials comparing TRI with transfemoral access in STEMI.
  • Analysis of factors influencing TRI adoption rates and clinical practice barriers.

Main Results:

  • TRI is associated with significantly reduced periprocedural bleeding and lower mortality compared to transfemoral access in STEMI.
  • TRI offers additional benefits including enhanced patient comfort, shorter hospital stays, and reduced costs.
  • Despite evidence, TRI adoption in the US remains slow due to clinical practice barriers and uncertainty about mortality reduction causality.

Conclusions:

  • Transradial percutaneous intervention (TRI) is a safe and effective access site for STEMI, demonstrating reduced bleeding and mortality.
  • Increased training in cardiovascular fellowship programs and post-fellowship courses is crucial for widespread TRI implementation.
  • A call to action is proposed to overcome barriers and promote greater use of TRI in STEMI management.

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