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Systematic use of transradial PCI in patients with ST-segment elevation myocardial infarction: a call to "arms"
Mackram F Eleid1, Charanjit S Rihal, Rajiv Gulati
1Division of Cardiovascular Diseases, Mayo Clinic College of Medicine, Rochester, Minnesota.
Insights
Transradial percutaneous intervention (TRI) is increasingly recommended for ST-segment elevation myocardial infarction (STEMI) patients, offering reduced bleeding and mortality. Wider adoption is encouraged despite historical concerns and slow implementation.
Area of Science:
- Cardiology
- Interventional Cardiology
- Vascular Access
Background:
- Transradial percutaneous intervention (TRI) is gaining support as a preferred access site for ST-segment elevation myocardial infarction (STEMI).
- Historically, concerns regarding procedure time, door-to-device time, and operator experience limited TRI use in STEMI.
- Growing evidence highlights the link between periprocedural bleeding and mortality in acute coronary syndromes, increasing interest in TRI for bleeding reduction.
Purpose of the Study:
- To review the current evidence supporting transradial percutaneous intervention (TRI) in STEMI patients.
- To address barriers to TRI adoption and advocate for its increased implementation in STEMI treatment.
Main Methods:
- Systematic review of registry data, meta-analyses, and randomized control trials comparing TRI with transfemoral access in STEMI.
- Analysis of factors influencing TRI adoption rates and clinical practice barriers.
Main Results:
- TRI is associated with significantly reduced periprocedural bleeding and lower mortality compared to transfemoral access in STEMI.
- TRI offers additional benefits including enhanced patient comfort, shorter hospital stays, and reduced costs.
- Despite evidence, TRI adoption in the US remains slow due to clinical practice barriers and uncertainty about mortality reduction causality.
Conclusions:
- Transradial percutaneous intervention (TRI) is a safe and effective access site for STEMI, demonstrating reduced bleeding and mortality.
- Increased training in cardiovascular fellowship programs and post-fellowship courses is crucial for widespread TRI implementation.
- A call to action is proposed to overcome barriers and promote greater use of TRI in STEMI management.
Abstract:
A growing body of evidence now supports the use of transradial percutaneous intervention (TRI) as the preferred access site for the treatment of patients with ST-segment elevation myocardial infarction (STEMI). Historically, TRI has been avoided in the STEMI population due to concerns over longer procedure time, longer door-to-device time, higher crossover rates, and the experience level required with TRI compared with transfemoral access. However, in recent years, recognition of the impact of periprocedural bleeding on mortality in patients with acute coronary syndromes has garnered interest in the utility of TRI as an established method to reduce bleeding. Registry data, meta-analyses, and randomized control trials all similarly demonstrate that TRI is associated with reduced periprocedural bleeding and lower mortality compared with transfemoral access in the STEMI population. Additional benefits of TRI include enhanced patient comfort, reduced hospital length of stay, and reduced cost. Despite the evidence, trends in use of TRI in the United States have shown a slow adoption rate as a result of multiple barriers in clinical practice and doubts about the mechanism and causal relationship of mortality reduction with TRI. We summarize the current evidence and propose a call to action to foster training of TRI in cardiovascular fellowship programs and post-fellowship courses, and for more widespread implementation of TRI in STEMI patients.
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