Giant calvarial desmoplastic fibroblastoma

Area of Science:

• Oncology
• Pathology
• Dermatology

Background:

• Desmoplastic fibroblastoma is a rare soft tissue tumor.
• Giant variants are exceptionally uncommon, particularly in the calvarium.

Observation:

• A 20-year-old woman presented with a giant desmoplastic fibroblastoma of the calvarium, first noted at age 5.
• The tumor's long-standing presence and significant size posed unique clinical challenges.

Findings:

• Histopathological examination is crucial for differentiating desmoplastic fibroblastoma from other spindle cell neoplasms.
• The case highlights the slow-growing nature and potential for significant growth of this tumor type.

Implications:

• This case expands the understanding of giant desmoplastic fibroblastoma presentation and natural history.
• It underscores the importance of considering rare tumors in the differential diagnosis of cranial masses.
• Further research into optimal management strategies for large or recurrent desmoplastic fibroblastomas is warranted.