Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Local Anesthetics: Differential Sensitivity of Nerve Fibers01:24

Local Anesthetics: Differential Sensitivity of Nerve Fibers

1.5K
Local anesthetics (LAs) block the sodium channels of nerve trunks, sensory nerve endings, and neuromuscular junctions. Although LAs can block all kinds of nerves, the sensitivity of nerve fibers differs according to nerve types and structures. LAs are known to block myelinated fibers faster than unmyelinated ones. Also, they block pain or sensory neurons at low concentrations without affecting the motor neurons involved in muscle contractions. This helps relieve labor pain without affecting the...
1.5K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Screw-Lock: A Novel Technique to Secure Burr Hole Base Ring in DBS Surgery.

Surgical innovation·2026
Same author

Corrigendum to "Revisiting subcallosal cingulate deep brain stimulation for depression: Long-term safety and effectiveness outcomes from a pooled analysis of 172 implanted patients" [Brain Stimul 18 (2025) 1632-1640].

Brain stimulation·2026
Same author

The History of Neurological Surgery at the University of Illinois Chicago.

World neurosurgery·2026
Same author

Development of an Educational Curriculum for the Surgical Implantation of DBS Systems.

Neuromodulation : journal of the International Neuromodulation Society·2026
Same author

Vagus Nerve Stimulation for Neuromodulation: Evolution from Bench to Bedside.

Neurology international·2026
Same author

Commentary: Long-Term Outcomes of Dorsal Root Entry Zone Lesioning for Neuropathic Pain Following Brachial Plexus Avulsion: A 10-Year Follow-up Study.

Neurosurgery·2025

Related Experiment Video

Updated: Feb 17, 2026

Open-Source Real-Time Closed-Loop Electrical Threshold Tracking for Translational Pain Research
10:28

Open-Source Real-Time Closed-Loop Electrical Threshold Tracking for Translational Pain Research

Published on: April 21, 2023

1.8K

Peripheral nerve/field stimulation for neuropathic pain.

Milind Deogaonkar1, Konstantin V Slavin

  • 1Department of Neurosurgery, Ohio State University, Columbus, 480 Medical Center Drive, Columbus, OH 43210, USA.

Neurosurgery Clinics of North America
|November 23, 2013
PubMed
Summary

Peripheral nerve stimulation (PNS) and peripheral nerve field stimulation (PNFS) offer new hope for refractory pain. While promising, further randomized controlled studies are needed to confirm their effectiveness.

Keywords:
Chronic painField stimulationHeadacheNerve stimulationNeuropathic painOccipital neuralgiaPeripheral neuromodulationPost-herpetic neuralgia

More Related Videos

Implantation and Control of Wireless, Battery-free Systems for Peripheral Nerve Interfacing
07:13

Implantation and Control of Wireless, Battery-free Systems for Peripheral Nerve Interfacing

Published on: October 20, 2021

4.0K
Subcutaneous Trigeminal Nerve Field Stimulation for Refractory Facial Pain
09:35

Subcutaneous Trigeminal Nerve Field Stimulation for Refractory Facial Pain

Published on: May 10, 2017

19.7K

Related Experiment Videos

Last Updated: Feb 17, 2026

Open-Source Real-Time Closed-Loop Electrical Threshold Tracking for Translational Pain Research
10:28

Open-Source Real-Time Closed-Loop Electrical Threshold Tracking for Translational Pain Research

Published on: April 21, 2023

1.8K
Implantation and Control of Wireless, Battery-free Systems for Peripheral Nerve Interfacing
07:13

Implantation and Control of Wireless, Battery-free Systems for Peripheral Nerve Interfacing

Published on: October 20, 2021

4.0K
Subcutaneous Trigeminal Nerve Field Stimulation for Refractory Facial Pain
09:35

Subcutaneous Trigeminal Nerve Field Stimulation for Refractory Facial Pain

Published on: May 10, 2017

19.7K

Area of Science:

  • Neuromodulation
  • Pain Management
  • Neurosurgery

Background:

  • Peripheral nerve stimulation (PNS) and peripheral nerve field stimulation (PNFS) are evolving neuromodulatory treatments.
  • Percutaneous stimulation technology has advanced, expanding indications for refractory pain.
  • Successful treatment depends on patient selection and optimal device placement.

Purpose of the Study:

  • To review the current status and potential of PNS and PNFS for refractory pain.
  • To highlight the importance of patient selection and device parameters.
  • To identify the need for future research.

Main Methods:

  • Review of existing literature, including case reports and retrospective studies.
  • Analysis of technological advancements in electrodes and implantable pulse generators.
  • Discussion of patient selection criteria for neuromodulatory therapies.

Main Results:

  • PNS and PNFS show promise in managing medically refractory pain.
  • Current evidence is largely based on case reports and retrospective data.
  • Successful outcomes are linked to appropriate patient, electrode, and generator selection.

Conclusions:

  • PNS and PNFS represent a viable therapeutic option for refractory pain.
  • Further high-quality, randomized controlled studies are essential.
  • This emerging technology requires rigorous evaluation to establish its full potential.