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Proximity of TCR and its CD8 coreceptor controls sensitivity of T cells

Jessica G Borger1, Rose Zamoyska1, Dmitry M Gakamsky2

  • 1Institute of Immunology and Infection Research, The University of Edinburgh, Edinburgh EH9 3JT, UK.

Immunology Letters
|November 23, 2013
PubMed

Keywords:
APCAgAntigen recognitionCD8 coreceptorCTLEMFCSFluorescence lifetime cross-correlation microscopyFunctional avidity maturationLNNSOMT cell receptorT cell receptor signallingT cell sensitivityTCRantigenantigen presenting cellcytotoxic T cell lymphocyteelectron microscopyfetal calf serumlymph nodemAbmonoclonal antibodynear-field scanning optical microscopy

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