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Related Experiment Video

Updated: May 5, 2026

Novel Object Recognition Test for the Investigation of Learning and Memory in Mice
08:52

Novel Object Recognition Test for the Investigation of Learning and Memory in Mice

Published on: August 30, 2017

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Object recognition test in mice.

Marianne Leger1, Anne Quiedeville, Valentine Bouet

  • 11] Groupe Mémoire et Plasticité comportementale (GMPc), Université de Caen Basse-Normandie, Caen, France. [2].

Nature Protocols
|November 23, 2013
PubMed
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This study standardizes the object recognition test for mice, a common behavioral test. The new protocol reduces variability and allows for better comparison of recognition memory results across studies.

Area of Science:

  • Neuroscience
  • Animal Behavior

Background:

  • The object recognition test is a widely used behavioral assay in mice to assess recognition memory.
  • Increasing variability in experimental procedures has hindered inter-study comparisons.

Purpose of the Study:

  • To provide a standardized protocol for the object recognition test in mice.
  • To reduce inter-individual variability in behavioral test results.

Main Methods:

  • Standardized object recognition test protocol with defined exploration time criteria.
  • Description of three variants based on habituation phase duration (3 days, 1 day, or no habituation).
  • Protocol adaptable for different experimental time constraints.

Main Results:

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Novel Object Recognition and Object Location Behavioral Testing in Mice on a Budget
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A Behavioral Test Battery for the Repeated Assessment of Motor Skills, Mood, and Cognition in Mice
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Related Experiment Videos

Last Updated: May 5, 2026

Novel Object Recognition Test for the Investigation of Learning and Memory in Mice
08:52

Novel Object Recognition Test for the Investigation of Learning and Memory in Mice

Published on: August 30, 2017

76.4K
Novel Object Recognition and Object Location Behavioral Testing in Mice on a Budget
05:57

Novel Object Recognition and Object Location Behavioral Testing in Mice on a Budget

Published on: November 20, 2018

60.0K
A Behavioral Test Battery for the Repeated Assessment of Motor Skills, Mood, and Cognition in Mice
07:18

A Behavioral Test Battery for the Repeated Assessment of Motor Skills, Mood, and Cognition in Mice

Published on: March 2, 2019

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  • The protocol introduces a selection criterion based on minimal exploration time to reduce variability.
  • The described variants allow the test to be completed in 1, 2, or 4 days.

    • Conclusions:

    • This standardized protocol enhances the reliability and comparability of object recognition test results.
    • The protocol offers flexibility for researchers while maintaining standardization.