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Updated: May 5, 2026

Site-Directed φC31-Mediated Integration and Cassette Exchange in Anopheles Vectors of Malaria
Published on: February 2, 2021
Homozygous translocations in Anopheles albimanus
P E Kaiser1, J A Seawright, M Q Benedict
1Insects Affecting Man and Animals Research Laboratory, Agricultural Research Service, USDA, 32604, Gainesville, FL, USA.
Abstract:
Four homozygous, autosomal translocation stocks were established in Anopheles albimanus, which is an important vector of malaria in Central America. When inbred, the fertility of these homozygous translocation stocks ranged from 87.4 to 92.5%, and similar fertilities were observed in outcrosses to a normal strain. The chromosomal breakpoints for these four translocations were located close to the centromeres. The sterility in heterozygous translocation males was consistently higher than that observed for females.
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