Related Experiment Video
Updated: May 5, 2026

Spontaneous Murine Model of Anaplastic Thyroid Cancer
Published on: February 3, 2023
Breast metastases to thyroid gland
Mike S Nguyen1, Daniel T Ginat, Ellen J Giampoli
1*Department of Imaging Sciences, University of Rochester Medical Center, Rochester, NY; †Department of Radiology, Massachusetts General Hospital, Boston, MA; and ‡Department of Pathology and Laboratory Medicine, University of Rochester Medical Center, Rochester, NY.
Abstract:
Metastases to the thyroid gland are uncommon. We present the sonographic features of metastatic breast adenocarcinoma to the thyroid in a 67-year-old woman. The lesion measured up to 0.9 cm in diameter, contained an echogenic focus with associated ring-down, and was predominantly cystic, thereby resembling a benign nodule. Because of the patient's history of breast adenocarcinoma, the nodule nevertheless underwent fine-needle aspiration. The unusual appearance of the thyroid nodule underscores the importance of considering patient history in deciding whether obtaining tissue diagnosis of thyroid nodules is warranted.
Related Concept Videos
Hyperthyroidism I: Introduction
Hyperthyroidism II: Pathophysiology
Graves Disease II: Pathophysiology
Goiter
The Thyroid Gland
The follicles have a central cavity lined by simple cuboidal to squamous epithelial cells called follicular cells. These cells produce the glycoprotein...
Graves' Disease I: Introduction

