Related Experiment Video
Updated: May 5, 2026

The Insect Galleria mellonella as a Powerful Infection Model to Investigate Bacterial Pathogenesis
Published on: December 11, 2012
Leaf phenolic inhibition of gypsy moth nuclear polyhedrosis virus Role of polyhedral inclusion body aggregation
S T Keating1, M D Hunter, J C Schultz
1Pesticide Research Laboratory, Pennsylvania State University, 16802, University Park, Pennsylvania.
Abstract:
Bioassays with nuclear polyhedrosis virus (NPV) administered to gypsy moth larvae on leaf disks from various tree species reveal strong viral inhibition by some tree species. Phenolic extracts from inhibitory tree leaves cause virus polyhedral inclusion bodies (PIBs) to form large aggregations. However, aggregated PIBs treated with leaf extracts and administered to larvae on laboratory diet (without phenolics) retain virulence. Our results suggest that leaf phenolics, especially hydrolyzable tannins, inhibit NPV infection, but may not act via aggregations formed in the foregut.
More Related Videos
06:02Arbovirus Infections As Screening Tools for the Identification of Viral Immunomodulators and Host Antiviral Factors
Published on: September 13, 2018
10:14Double-stranded RNA Oral Delivery Methods to Induce RNA Interference in Phloem and Plant-sap-feeding Hemipteran Insects
Published on: May 4, 2018
Related Concept Videos
Inhibitors of Viral Protein Synthesis
Inhibitors of Bacterial DNA Synthesis