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[Analgesics, antipyretics and non-steroidal anti-inflammatory drugs in pediatric prescriptions]

Tânia Regina Ferreira, Silvio Barberato Filho, Adriano Ferreti Borgatto

    Ciencia & Saude Coletiva
    |November 23, 2013
    PubMed

    Insights

    Most pediatric prescriptions for pain relievers and anti-inflammatory drugs lack regulatory approval and evidence. Over 95% of these prescriptions, in both public and private sectors, contain errors in dosage, frequency, or duration.

    Area of Science:

    • Pediatric pharmacology
    • Drug utilization research
    • Evidence-based medicine

    Context:

    • Analgesic, antipyretic, and non-steroidal anti-inflammatory drugs (NSAIDs) are frequently used in children.
    • Pediatric drug prescriptions are often influenced by factors undermining rational use.
    • Regulatory agency approval and scientific evidence do not always support common pediatric drug use.

    Purpose:

    • To evaluate the utilization of analgesic, antipyretic, and NSAIDs in children within both public (Unified Health System - SUS) and private (Non-SUS) healthcare sectors.
    • To assess the appropriateness of drug prescriptions based on age, dosage, frequency, and duration of treatment.
    • To identify differences or similarities in prescribing patterns between public and private healthcare settings.

    Summary:

    • A study analyzed 150 pediatric prescriptions (101 SUS, 49 Non-SUS) and interviewed caregivers across 18 locations.
    • Appropriate age-based prescribing occurred in only 21.8% (SUS) and 29.6% (Non-SUS) of cases.
    • Over 95% of all prescriptions exhibited errors in dosage, frequency, or duration, failing to meet rational use criteria.

    Impact:

    • Findings indicate widespread issues with rational drug use for common pediatric medications.
    • There are no significant differences in prescription quality between public and private sectors.
    • Highlights the need for improved guidelines and education for healthcare providers prescribing these medications to children.

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