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Related Experiment Video

Updated: May 5, 2026

Occlusion of the Great and Small Saphenous Vein Using Copolymeric Glue Based on N-Butyl Cyanoacrylate and Methacryloxy Sulfolane

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[Leg swelling].

S M Schellong¹, U Wollina, L Unger

¹Medizinische Klinik 2, Krankenhaus Dresden-Friedrichstadt, Städtisches Klinikum, Friedrichstr. 41, 01067, Dresden, Deutschland, schellong-se@khdf.de.

|November 23, 2013

Summary

This summary is machine-generated.

Leg swelling has many causes, including vein and lymphatic issues, fluid overload, and low protein. Diagnosis often relies on patient history and physical exam, reducing the need for further tests.

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Area of Science:

Vascular Medicine
Nephrology
Cardiology

Context:

Leg swelling is a common symptom with diverse underlying causes.
Understanding these causes is crucial for accurate diagnosis and effective management.
Differential diagnosis involves considering various systemic and local pathologies.

Purpose:

To review the pathophysiology and clinical features of common leg swelling causes.
To provide a guide for the differential diagnosis of leg edema.
To highlight key mechanisms like venous/lymphatic issues, volume overload, and oncotic pressure.

Summary:

Frequent causes include deep vein thrombosis, chronic venous insufficiency, lymphedema, cardiac failure, hypoproteinemia, and drug-induced edema.
Lipedema is an important differential diagnosis to consider.
Most cases are diagnosed through thorough history and physical examination, with further tests reserved for a minority.

Impact:

Aids clinicians in diagnosing the diverse causes of leg swelling.
Improves patient management by identifying underlying conditions.
Contributes to the medical literature on edema pathophysiology and clinical presentation.